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How to get fromMayo Clinic to Casperby bus, plane, or car

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There are 8 ways to get from Mayo Clinic to Casper by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Minneapolis–Saint Paul International Airport, fly to Casper

    best
    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Casper (CPR)plane plane MSP - CPR
    7h
    $162–615

  2. Fly Rochester to Casper

    cheapest
    1. Fly from Rochester (RST) to Casper (CPR)plane plane RST - CPR
    8h 9m
    $103–512

  3. Bus

    1. Take the bus from Rochester to Minneapolisbus bus
    2. Take the bus from Minneapolis to Billingsbus bus
    3. Take the bus from Billings, MT to Casper Amtrak Stationbus bus
    26h 38m
    $311–432

  4. Drive 803.5 mi

    1. Drive from Mayo Clinic to Caspercar car 803.5 mi
    13h 8m
    $147–212

  5. Drive to The Eastern Iowa Airport, fly to Casper

    1. Drive from Mayo Clinic to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Casper (CPR)plane plane CID - CPR
    8h 22m
    $134–501

  6. Drive to Fort Dodge Municipal Airport, fly to Casper

    1. Drive from Mayo Clinic to Fort Dodge Municipal Airport (FOD)car car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Casper (CPR)plane plane FOD - CPR
    8h
    $124–481

  7. Fly Rochester to Rapid City, drive

    1. Fly from Rochester (RST) to Rapid City (RAP)plane plane RST - RAP
    2. Drive from Rapid-City-Airport-RAP to Caspercar car
    11h 1m
    $111–477

  8. Bus to Minneapolis–Saint Paul International Airport, fly to Rapid City, drive

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Rapid City (RAP)plane plane MSP - RAP
    3. Drive from Rapid-City-Airport-RAP to Caspercar car
    8h 30m
    $165–540

Mayo Clinic to Casper by foot and bus

Calendar1Weekly Services
Duration26h 38mAverage Duration
Ticket$311Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Casper.ExpandLaunch map view
  • Distance: 762.7 mi
  • Duration: 7h

What companies run services between Mayo Clinic, MN, USA and Casper, WY, USA?

You can take a vehicle from Mayo Clinic to Casper Amtrak Station via Rochester, Minneapolis, and Billings, MT in around 26h 38m. Alternatively, United Airlines, Delta, and American Airlines fly from Rochester (RST) to Casper (CPR) 5 times a day.

Airlines
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