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How to get fromMayo Clinic to Destinby bus, plane, taxi, train, or car

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There are 9 ways to get from Mayo Clinic to Destin by bus, plane, taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Minneapolis–Saint Paul International Airport, fly to Destin–Fort Walton Beach Airport

    best
    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Destin–Fort Walton Beach Airport (VPS)plane plane MSP - VPS
    5h 29m
    $200–705

  2. Fly Rochester to Destin–Fort Walton Beach Airport

    cheapest
    1. Fly from Rochester (RST) to Destin–Fort Walton Beach Airport (VPS)plane plane RST - VPS
    6h 32m
    $141–582

  3. Bus, taxi

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    5. Take the bus from La Grange Bus Station to Mobilebus bus
    6. Take the bus from Loxley to Crestviewbus bus
    7. Take the taxi from Crestview to Destintaxi taxi
    35h 21m
    $382–596

  4. Bus, train, taxi via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Pascagoulatrain train
    5. Take the bus from Pascagoula to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    36h 52m
    $475–914

  5. Drive  1,172.6 mi

    1. Drive from Mayo Clinic to Destincar car 1,172.6 mi
    21h 3m
    $214–310

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Northwest Florida Beaches International Airport, taxi

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Northwest Florida Beaches International Airport (ECP)plane plane MSP - ECP
    3. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    7h 43m
    $310–830

  7. Fly Rochester to Northwest Florida Beaches International Airport, taxi

    1. Fly from Rochester (RST) to Northwest Florida Beaches International Airport (ECP)plane plane RST - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    9h 2m
    $241–697

  8. Fly Rochester to Pensacola International Airport, taxi

    1. Fly from Rochester (RST) to Pensacola International Airport (PNS)plane plane RST - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    9h 5m
    $196–577

  9. Bus, train, taxi

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    5. Take the bus from Mobile to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    38h 15m
    $524–1,074

Minneapolis–Saint Paul International Airport (MSP) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar5Weekly Planes
Duration4h 2mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Destin.ExpandLaunch map view
  • Distance: 1,151.7 mi
  • Duration: 5h 29m

What companies run services between Mayo Clinic, MN, USA and Destin, FL, USA?

Delta and Sun Country Airlines fly from Rochester (RST) to Destin–Fort Walton Beach Airport (VPS) 3 times a week.

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