There are 8 ways to get from Mayo Clinic to Dyer by plane, train, bus, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Rochester to Chicago O'Hare International Airport, train
best- Fly from Rochester (RST) to Chicago O'Hare International Airport (ORD)plane RST - ORD
- Take the train from Van Buren St. to Hammond Gatewaytrain
- Take the train from Hammond Gateway to Munster Dyer Stationtrain
6h 4m$61–310Bus, train via Milwaukee
- Take the bus from Rochester to Milwaukeebus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Dyer Stationtrain
10h 24m$108–187Bus, train
- Take the bus from Rochester to St. Paulbus
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Dyer Stationtrain
12h 12m$154–360Drive 372.4 mi
- Drive from Mayo Clinic to Dyercar 372.4 mi
6h 24m$68–99Bus to Minneapolis–Saint Paul International Airport, fly to Chicago O'Hare International Airport, train
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago O'Hare International Airport (ORD)plane MSP - ORD
- Take the train from Van Buren St. to Hammond Gatewaytrain
- Take the train from Hammond Gateway to Munster Dyer Stationtrain
7h 5m$305–833Bus to Minneapolis–Saint Paul International Airport, fly to Chicago Midway International Airport, train
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago Midway International Airport (MDW)plane MSP - MDW
- Take the train from Van Buren St. to Hammond Gatewaytrain
- Take the train from Hammond Gateway to Munster Dyer Stationtrain
6h 57m$135–483Bus, train #2
- Take the bus from Rochester to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to Dyer Stationtrain
11h 1m$95–165Bus
- Take the bus from Rochester to Madisonbus Jefferson Lines 965
- Take the bus from Madison to Chicago Bus Stationbus FlixBus 2548 / ...
12h 12m$102–146
Rochester (RST) to Chicago O'Hare International Airport (ORD) flights
Comparing Your Travel Options
The cheapest way to get from Mayo Clinic to Dyer is to drive which costs $65 - $100 and takes 6h 24m.
The fastest way to get from Mayo Clinic to Dyer is to fly and train which takes 6h 4m and costs $60 - $310.
No, there is no direct bus from Mayo Clinic to Dyer. However, there are services departing from Rochester and arriving at Torrence Ave & Kalvelage Dr via Madison, Jefferson & Harrison and Hegewisch South Shore Station. The journey, including transfers, takes approximately 12h 12m.
The distance between Mayo Clinic and Dyer is 326 miles. The road distance is 374.6 miles.
The best way to get from Mayo Clinic to Dyer without a car is to bus and train via Milwaukee which takes 10h 24m and costs $100 - $190.
It takes approximately 6h 4m to get from Mayo Clinic to Dyer, including transfers.
Mayo Clinic to Dyer bus services, operated by Jefferson Lines, depart from Rochester station.
Mayo Clinic to Dyer bus services, operated by Jefferson Lines, arrive at Madison station.
Yes, the driving distance between Mayo Clinic to Dyer is 375 miles. It takes approximately 6h 24m to drive from Mayo Clinic to Dyer.
There are 133+ hotels available in Dyer.
What companies run services between Mayo Clinic, MN, USA and Dyer, IN, USA?
You can take a vehicle from Mayo Clinic to Dyer via Rochester, Madison, Chicago Bus Station, Jefferson & Harrison, Randolph & Michigan, Millennium Station, Hegewisch, Hegewisch South Shore Station, and Torrence Ave & Kalvelage Dr in around 12h 12m.
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $45–310
Flights from Minneapolis–Saint Paul International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $60–400
- Website
- southwest.com
Flights from Minneapolis–Saint Paul International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $60–400
- Website
- aa.com
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $35–240
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $45–310
- Website
- united.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $45–310
- Website
- suncountry.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 38m
- When
- Wednesday and Friday
- Estimated price
- $45–310
Train from Van Buren St. to Hammond Gateway
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Schedules at
- Northern Indiana Commuter Transportation District
Train from Van Buren St. to Hammond Gateway
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Schedules at
- Northern Indiana Commuter Transportation District
Train from Van Buren St. to Hammond Gateway
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Schedules at
- Northern Indiana Commuter Transportation District
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Van Buren St. to Hammond Gateway
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- $7–8
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–8
Train from Hammond Gateway to Munster Dyer Station
- Ave. Duration
- 15 min
- Frequency
- Every 2 hours
- Estimated price
- $6–7
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $6–7
Train from Van Buren St. to Hammond Gateway
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- $7–8
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–8
Train from Hammond Gateway to Munster Dyer Station
- Ave. Duration
- 15 min
- Frequency
- Every 2 hours
- Estimated price
- $6–7
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $6–7
Train from Van Buren St. to Hammond Gateway
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- $7–8
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–8
Train from Hammond Gateway to Munster Dyer Station
- Ave. Duration
- 15 min
- Frequency
- Every 2 hours
- Estimated price
- $6–7
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $6–7
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $23–60
- Website
- Amtrak
Train from Chicago Union Station to Dyer Station
- Ave. Duration
- 59 min
- Frequency
- 3 times a week
- Estimated price
- $7–20
- Website
- Amtrak
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 32m
- Frequency
- 3 times a day
- Estimated price
- $110–290
- Website
- Amtrak
Train from Chicago Union Station to Dyer Station
- Ave. Duration
- 59 min
- Frequency
- 3 times a week
- Estimated price
- $7–20
- Website
- Amtrak
Train from Chicago Union Station to Dyer Station
- Ave. Duration
- 59 min
- Frequency
- 3 times a week
- Estimated price
- $7–20
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to Milwaukee
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Bus from Rochester to St. Paul
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Madison to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- Twice daily
- Estimated price
- $26–40
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Madison to Chicago Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $28–45
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide










