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How to get fromMayo Clinic to Escanababy plane, bus, car, bus (Greyhound), or train

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There are 7 ways to get from Mayo Clinic to Escanaba by plane, bus, car, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Delta County Airport

    best
    1. Fly from Rochester (RST) to Delta County Airport (ESC)plane plane RST - ESC
    5h 32m
    $68–399

  2. Drive  363.7 mi

    cheapest
    1. Drive from Mayo Clinic to Escanabacar car 363.7 mi
    7h 25m
    $67–96

  3. Bus via Milwaukee

    1. Take the bus from Rochester to Milwaukeebus bus Jefferson Lines 965
    2. Take the bus from Milwaukee to Escanababus bus It 58
    12h 14m
    $120–185

  4. Bus to Minneapolis–Saint Paul International Airport, fly to Delta County Airport

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Delta County Airport (ESC)plane plane MSP - ESC
    3h 52m
    $127–472

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Iron Mountain, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Iron Mountain (IMT)plane plane MSP - IMT
    3. Take the bus from Iron Mountain to Escanababus bus
    6h 8m
    $145–503

  6. Bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Take the bus from Minneapolis Bus Station to Green Bay Transit Centerbus bus
    3. Take the bus from Green Bay to Escanababus bus
    13h 9m
    $132–186

  7. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Milwaukeetrain train
    3. Take the bus from Milwaukee to Escanababus bus
    14h 47m
    $249–408

Rochester (RST) to Delta County Airport (ESC) flights

Calendar5Weekly Planes
Duration4h 2mAverage Duration
Ticket$53Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mayo Clinic to Escanaba.ExpandLaunch map view
  • Distance: 304.8 mi
  • Duration: 5h 32m

What companies run services between Mayo Clinic, MN, USA and Escanaba, MI, USA?

Delta flies from Rochester (RST) to Delta County Airport (ESC) 5 times a week. Alternatively, you can take a vehicle from Mayo Clinic to Escanaba via Rochester, Milwaukee, and Escanaba in around 12h 14m.

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