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How to get fromMayo Clinic to Escanababy plane, bus, or car

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There are 4 ways to get from Mayo Clinic to Escanaba by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Rochester

    best
    1. Fly from Rochester (RST) to Delta County Airport (ESC)plane plane RST - ESC
    6h 20m
    $118–659

  2. Drive 363.7 mi

    cheapest
    1. Drive from Mayo Clinic to Escanabacar car 363.7 mi
    7h 25m
    $67–96

  3. Bus

    1. Take the bus from Rochester, MN to La Crossebus bus
    2. Take the bus from La Crosse Grand River Station to Green Bay stationbus bus
    3. Take the bus from Green Bay, WI - Transit to Escanababus bus
    11h 39m
    $102–142

  4. Bus to Minneapolis–Saint Paul International Airport, fly

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Delta County Airport (ESC)plane plane MSP - ESC
    3h 48m
    $122–422

Rochester (RST) to Delta County Airport (ESC) flights

Calendar12Weekly Planes
Duration7h 41mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Escanaba.ExpandLaunch map view
  • Distance: 304.8 mi
  • Duration: 6h 20m

What companies run services between Mayo Clinic, MN, USA and Escanaba, MI, USA?

Delta flies from Rochester (RST) to Delta County Airport (ESC) twice daily. Alternatively, you can take a vehicle from Mayo Clinic to Escanaba via Rochester, MN, La Crosse, La Crosse Grand River Station, Green Bay, WI - Transit, and Escanaba in around 11h 39m.

Airlines
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