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How to get fromMayo Clinic to Escanababy plane, bus, or car

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There are 6 ways to get from Mayo Clinic to Escanaba by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Delta County Airport

    best
    1. Fly from Rochester (RST) to Delta County Airport (ESC)plane plane RST - ESC
    5h 25m
    $68–399

  2. Drive  363.7 mi

    cheapest
    1. Drive from Mayo Clinic to Escanabacar car 363.7 mi
    7h 25m
    $67–96

  3. Bus

    1. Take the bus from Rochester to La Crossebus bus
    2. Take the bus from La Crosse Grand River Station to Green Bay stationbus bus
    3. Take the bus from Green Bay, WI - Transit to Escanababus bus
    11h 54m
    $102–142

  4. Bus to Minneapolis–Saint Paul International Airport, fly to Delta County Airport

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Delta County Airport (ESC)plane plane MSP - ESC
    3h 47m
    $127–472

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Iron Mountain, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Iron Mountain (IMT)plane plane MSP - IMT
    3. Take the bus from Iron Mountain to Escanababus bus
    6h 10m
    $145–493

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Sawyer International Airport, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Sawyer International Airport (MQT)plane plane MSP - MQT
    3. Take the bus from Gwinn to Escanababus bus
    5h 56m
    $153–522

Rochester (RST) to Delta County Airport (ESC) flights

Calendar5Weekly Planes
Duration3h 55mAverage Duration
Ticket$53Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mayo Clinic to Escanaba.ExpandLaunch map view
  • Distance: 304.8 mi
  • Duration: 5h 25m

What companies run services between Mayo Clinic, MN, USA and Escanaba, MI, USA?

Delta flies from Rochester (RST) to Delta County Airport (ESC) 5 times a week. Alternatively, you can take a vehicle from Mayo Clinic to Escanaba via Rochester, La Crosse Grand River Station, Green Bay, WI - Transit, and Escanaba in around 11h 54m.

Airlines
Bus operators

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