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How to get fromMayo Clinic to Fort Wayneby plane, bus, train, car, or bus (Flixbus, Greyhound)

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There are 6 ways to get from Mayo Clinic to Fort Wayne by plane, bus, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Rochester

    best
    1. Fly from Rochester (RST) to Fort Wayne International Airport (FWA)plane plane RST - FWA
    5h 25m
    $91–422

  2. Bus via Chicago

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago to Fort Wayne, INbus bus
    15h 3m
    $98–191

  3. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Elkhart Amtrak Stationtrain train
    4. Take the bus from Goshen, IN to Fort Wayne, INbus bus
    17h 31m
    $162–382

  4. Drive  502.8 mi

    1. Drive from Mayo Clinic to Fort Waynecar car 502.8 mi
    8h 55m
    $92–133

  5. Bus to Minneapolis–Saint Paul International Airport, fly

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Fort Wayne International Airport (FWA)plane plane MSP - FWA
    4h 29m
    $155–525

  6. Bus

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from Madison to Chicago Bus Stationbus bus
    3. Take the bus from Chicago to Fort Wayne, INbus bus
    15h 29m
    $97–176

Mayo Clinic to Fort Wayne by foot and bus

Calendar7Weekly Services
Duration15h 3mAverage Duration
Ticket$98Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mayo Clinic to Fort Wayne.ExpandLaunch map view
  • Distance: 444.5 mi
  • Duration: 5h 25m

What companies run services between Mayo Clinic, MN, USA and Fort Wayne, IN, USA?

United Airlines, Delta, and American Airlines fly from Rochester (RST) to Fort Wayne International Airport (FWA) every 4 hours. Alternatively, you can take a vehicle from Mayo Clinic to Coldwater at Stratton via Rochester, Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, Chicago, Fort Wayne, IN, and Central Station - Bay A in around 15h 3m.

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