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How to get fromMayo Clinic to Grangerby plane, bus, train, car, or bus (Amtrak)

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There are 10 ways to get from Mayo Clinic to Granger by plane, bus, train, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to South Bend

    best
    1. Fly from Rochester (RST) to South Bend (SBN)plane plane RST - SBN
    5h 50m
    $91–417

  2. Drive  447.1 mi

    cheapest
    1. Drive from Mayo Clinic to Grangercar car 447.1 mi
    7h 28m
    $82–118

  3. Bus, train via Milwaukee

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Elkhart Amtrak Stationtrain train
    11h 29m
    $205–301

  4. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Elkhart Amtrak Stationtrain train
    13h 17m
    $339–519

  5. Bus to Minneapolis–Saint Paul International Airport, fly to South Bend

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to South Bend (SBN)plane plane MSP - SBN
    4h 17m
    $155–510

  6. Fly Rochester to Chicago O'Hare International Airport, train

    1. Fly from Rochester (RST) to Chicago O'Hare International Airport (ORD)plane plane RST - ORD
    2. Take the train from Van Buren St. to South Bend Airporttrain train
    6h 55m
    $92–349

  7. Bus to Minneapolis–Saint Paul International Airport, fly to Gerald R. Ford International Airport, drive

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Gerald R. Ford International Airport (GRR)plane plane MSP - GRR
    3. Drive from Grand-Rapids-Airport-GRR to Grangercar car
    5h 51m
    $133–487

  8. Bus

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Elkhart Amtrak Stationbus bus
    12h 6m

  9. Bus, train #2

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Van Buren St. to South Bend Airporttrain train
    12h 18m
    $137–204

  10. Bus, train #3

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from Madison to Chicago Bus Stationbus bus
    3. Take the train from Millennium Station to South Bend Airporttrain train
    12h 59m
    $138–194

Rochester (RST) to South Bend (SBN) flights

Calendar41Weekly Planes
Duration6h 34mAverage Duration
Ticket$52Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mayo Clinic to Granger.ExpandLaunch map view
  • Distance: 370.2 mi
  • Duration: 5h 50m

What companies run services between Mayo Clinic, MN, USA and Granger, IN, USA?

American Airlines and Delta fly from Rochester (RST) to South Bend (SBN) every 4 hours. Alternatively, you can take a vehicle from Mayo Clinic to Granger via Rochester, Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, Chicago Union Station, and Elkhart Amtrak Station in around 12h 6m.

Airlines
Train operators
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