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How to get fromMayo Clinic to Jacksonby plane, bus, car, or train

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There are 8 ways to get from Mayo Clinic to Jackson by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Mc Kellar-Sipes Regional Airport

    best
    1. Fly from Rochester (RST) to Mc Kellar-Sipes Regional Airport (MKL)plane plane RST - MKL
    9h 50m
    $201–787

  2. Drive 697.5 mi

    cheapest
    1. Drive from Mayo Clinic to Jacksoncar car 697.5 mi
    12h 23m
    $128–184

  3. Bus

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Water & Chicago - Circle K to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Tornado Bus Co - West Memphis to El Mezcal Grocery - Jackson, TNbus bus
    22h 18m
    $210–466

  4. Fly Rochester to Memphis, bus

    1. Fly from Rochester (RST) to Memphis (MEM)plane plane RST - MEM
    2. Take the bus from Tornado Bus Co - West Memphis to El Mezcal Grocery - Jackson, TNbus bus
    11h 48m
    $192–903

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Nashville, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Nashville (BNA)plane plane MSP - BNA
    3. Take the bus from Nashville to Jacksonbus bus
    10h 14m
    $489–1,054

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Memphis, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Memphis (MEM)plane plane MSP - MEM
    3. Take the bus from Tornado Bus Co - West Memphis to El Mezcal Grocery - Jackson, TNbus bus
    9h 59m
    $261–1,016

  7. Bus to Minneapolis–Saint Paul International Airport, fly to Mc Kellar-Sipes Regional Airport

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Mc Kellar-Sipes Regional Airport (MKL)plane plane MSP - MKL
    9h 4m
    $170–650

  8. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Milwaukeetrain train
    3. Take the bus from Water & Chicago - Circle K to Tornado Bus Co - West Memphisbus bus
    4. Take the bus from Tornado Bus Co - West Memphis to El Mezcal Grocery - Jackson, TNbus bus
    24h 51m
    $269–629

Rochester (RST) to Mc Kellar-Sipes Regional Airport (MKL) flights

Calendar12Weekly Planes
Duration10h 1mAverage Duration
Ticket$203Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Jackson.ExpandLaunch map view
  • Distance: 620.2 mi
  • Duration: 9h 50m

What companies run services between Mayo Clinic, MN, USA and Jackson, TN, USA?

United Airlines, Key Lime, and Delta fly from Rochester (RST) to Mc Kellar-Sipes Regional Airport (MKL) twice daily. Alternatively, you can take a vehicle from Mayo Clinic to Main St at Shannon St via Rochester, Milwaukee, Water & Chicago - Circle K, Tornado Bus Co - West Memphis, El Mezcal Grocery - Jackson, TN, and Lou’s Crawfish in around 22h 18m.

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