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How to get fromMayo Clinic to Kalamazooby plane, bus (Amtrak), bus, train, car, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Mayo Clinic to Kalamazoo by plane, bus (Amtrak), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Kalamazoo-Battle Creek International Airport

    best
    1. Fly from Rochester (RST) to Kalamazoo-Battle Creek International Airport (AZO)plane plane RST - AZO
    6h 51m
    $105–596

  2. Drive 490.9 mi

    cheapest
    1. Drive from Mayo Clinic to Kalamazoocar car 490.9 mi
    8h 11m
    $90–130

  3. Bus

    1. Take the bus from Rochester, MN to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Kalamazoobus bus
    12h 25m
    $134–209

  4. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kalamazootrain train
    13h 1m
    $199–399

  5. Fly Rochester to Chicago O'Hare International Airport, train

    1. Fly from Rochester (RST) to Chicago O'Hare International Airport (ORD)plane plane RST - ORD
    2. Take the train from Chicago Union Station to Kalamazootrain train
    6h 56m
    $112–539

  6. Fly Rochester to Gerald R. Ford International Airport, bus

    1. Fly from Rochester (RST) to Gerald R. Ford International Airport (GRR)plane plane RST - GRR
    2. Take the bus from Grand Rapids to Kalamazoo Metro Transitbus bus
    9h 4m
    $196–1,072

  7. Bus to Minneapolis–Saint Paul International Airport, fly to Gerald R. Ford International Airport, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Gerald R. Ford International Airport (GRR)plane plane MSP - GRR
    3. Take the bus from Grand Rapids to Kalamazoo Metro Transitbus bus
    7h 46m
    $174–728

  8. Bus, train via Madison

    1. Take the bus from Rochester, MN to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Kalamazootrain train
    12h 25m
    $124–229

  9. Bus via Lake Delton

    1. Take the bus from Rochester, MN to Wisconsin Dellsbus bus
    2. Take the bus from Wisconsin Dells to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Kalamazoo Bus Stopbus bus
    12h 38m
    $100–175

Mayo Clinic to Kalamazoo by foot and bus

Calendar3Weekly Services
Duration12h 25mAverage Duration
Ticket$134Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Kalamazoo.ExpandLaunch map view
  • Distance: 386.5 mi
  • Duration: 6h 51m

What companies run services between Mayo Clinic, MN, USA and Kalamazoo, MI, USA?

American Airlines and Delta fly from Rochester (RST) to Kalamazoo-Battle Creek International Airport (AZO) 4 times a day. Alternatively, you can take a vehicle from Mayo Clinic to Kalamazoo via Rochester, MN, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 12h 25m.

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