There are 9 ways to get from Mayo Clinic to Kalamazoo by bus (Amtrak), bus, train, car, plane, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Chicago
best- Take the bus from Rochester to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Union Station to Kalamazoobus
12h 5mFly Rochester to Kalamazoo-Battle Creek International Airport
cheapest- Fly from Rochester (RST) to Kalamazoo-Battle Creek International Airport (AZO)plane RST - AZO
10h 5m$53–379Bus, train
- Take the bus from Rochester to St. Paulbus
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Kalamazootrain
13h 16m$324–509Drive 490.9 mi
- Drive from Mayo Clinic to Kalamazoocar 490.9 mi
8h 12m$90–130Bus, train via Madison
- Take the bus from Rochester to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to Kalamazootrain
12h 5m$155–254Bus
- Take the bus from Rochester to Madisonbus
- Take the bus from Madison to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Kalamazoo Bus Stopbus
13h 28m$102–159Fly Rochester to Chicago O'Hare International Airport, train
- Fly from Rochester (RST) to Chicago O'Hare International Airport (ORD)plane RST - ORD
- Take the train from Chicago Union Station to Kalamazootrain
7h 2m$116–405Fly Rochester to Gerald R. Ford International Airport, bus
- Fly from Rochester (RST) to Gerald R. Ford International Airport (GRR)plane RST - GRR
- Take the bus from Grand Rapids to Kalamazoobus
9h 18m$70–405Bus to Minneapolis–Saint Paul International Airport, fly to Gerald R. Ford International Airport, bus
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Gerald R. Ford International Airport (GRR)plane MSP - GRR
- Take the bus from Grand Rapids to Kalamazoobus
7h 51m$129–508
Rochester (RST) to Kalamazoo-Battle Creek International Airport (AZO) flights
Comparing Your Travel Options
The cheapest way to get from Mayo Clinic to Kalamazoo is to drive which costs $85 - $130 and takes 8h 12m.
The fastest way to get from Mayo Clinic to Kalamazoo is to fly and train which takes 7h 2m and costs $110 - $410.
No, there is no direct bus from Mayo Clinic to Kalamazoo. However, there are services departing from Rochester and arriving at Kalamazoo via 250 N. Lake St - Madison UW Campus and Chicago Union Station. The journey, including transfers, takes approximately 12h 5m.
The distance between Mayo Clinic and Kalamazoo is 507 miles. The road distance is 493.7 miles.
The best way to get from Mayo Clinic to Kalamazoo without a car is to bus via Chicago which takes 12h 5m and costs .
It takes approximately 12h 5m to get from Mayo Clinic to Kalamazoo, including transfers.
Mayo Clinic to Kalamazoo bus services, operated by Jefferson Lines, depart from Rochester station.
The best way to get from Mayo Clinic to Kalamazoo is to bus via Chicago which takes 12h 5m and costs . Alternatively, you can fly, which costs $50 - $380 and takes 10h 5m.
Mayo Clinic to Kalamazoo bus services, operated by Jefferson Lines, arrive at Madison station.
Yes, the driving distance between Mayo Clinic to Kalamazoo is 494 miles. It takes approximately 8h 12m to drive from Mayo Clinic to Kalamazoo.
What companies run services between Mayo Clinic, MN, USA and Kalamazoo, MI, USA?
You can take a vehicle from Mayo Clinic to Kalamazoo via Rochester, Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 12h 5m. Alternatively, American Airlines and Delta fly from Rochester (RST) to Kalamazoo-Battle Creek International Airport (AZO) 4 times a day.
- Website
- delta.com
Flights from Rochester to Kalamazoo-Battle Creek International Airport via Minneapolis–Saint Paul International Airport, Detroit
- Ave. Duration
- 8h 40m
- When
- Every day
- Estimated price
- $70–400
Flights from Rochester to Gerald R. Ford International Airport via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $60–360
Flights from Rochester to Gerald R. Ford International Airport via Minneapolis–Saint Paul International Airport, Detroit
- Ave. Duration
- 8h 6m
- When
- Every day
- Estimated price
- $70–400
Flights from Minneapolis–Saint Paul International Airport to Gerald R. Ford International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $65–430
- Website
- aa.com
Flights from Rochester to Kalamazoo-Battle Creek International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 7h 59m
- When
- Every day
- Estimated price
- $50–340
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $35–240
Flights from Rochester to Gerald R. Ford International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $55–340
- Website
- southwest.com
Flights from Minneapolis–Saint Paul International Airport to Gerald R. Ford International Airport via Chicago Midway
- Ave. Duration
- 3h 25m
- When
- Sunday, Tuesday, Wednesday, Monday, Thursday, and Friday
- Estimated price
- $75–440
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 32m
- Frequency
- 3 times a day
- Estimated price
- $220–350
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Rochester to St. Paul
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 3 times a week
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Madison to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- Twice daily
- Estimated price
- $25–40
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Madison to Chicago Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $28–45
- Website
- Greyhound
Bus from Chicago Bus Station to Kalamazoo Bus Stop
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $23–40
- Website
- Greyhound
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Grand Rapids to Kalamazoo
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $10–24
- Website
- Indian Trails
Bus from Grand Rapids to Kalamazoo
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $10–24
- Website
- Indian Trails
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
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Booking & Getting There
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