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How to get fromMayo Clinic to Kansas Cityby shuttle, bus, car, or plane

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There are 5 ways to get from Mayo Clinic to Kansas City by shuttle, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle, bus

    best
    1. Take a shuttle bus from Rochester to Owatonna, MNshuttle bus S MN Conn 236 / ...
    2. Take the bus from Owatonna to Kansas Citybus bus Jefferson Lines 801 / ...
    9h 47m
    $96–167

  2. Drive 400.7 mi

    cheapest
    1. Drive from Mayo Clinic to Kansas Citycar car 400.7 mi
    6h 35m
    $74–106

  3. Fly from Rochester

    1. Fly from Rochester (RST) to Kansas City (MCI)plane plane RST - MCI
    6h 42m
    $91–587

  4. Bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus Groome Transportation
    2. Take the bus from Minneapolis-St. Paul to Kansas Citybus bus Jefferson Lines 803
    11h 47m
    $150–200

  5. Bus to Minneapolis–Saint Paul International Airport, fly

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Kansas City (MCI)plane plane MSP - MCI
    5h 27m
    $650–1,000

Rochester (RST) to Kansas City (MCI) flights

Calendar49Weekly Planes
Duration5h 13mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Kansas City.ExpandLaunch map view
  • Distance: 419.9 mi
  • Duration: 9h 47m

What companies run services between Mayo Clinic, MN, USA and Kansas City, MO, USA?

Delta, American Airlines, and United Airlines fly from Rochester (RST) to Kansas City (MCI) every 4 hours. Alternatively, you can take a vehicle from Mayo Clinic to Kansas City via Groome Transportation Office - Rochester, Minneapolis / St Paul Airport, and Minneapolis-St. Paul in around 11h 47m.

Airlines
Bus operators

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