What is the cheapest way to get from Mayo Clinic to La Crosse?

The cheapest way to get from Mayo Clinic to La Crosse is to drive which costs $13 - $20 and takes 1h 19m.

What is the fastest way to get from Mayo Clinic to La Crosse?

The fastest way to get from Mayo Clinic to La Crosse is to drive which takes 1h 19m and costs $13 - $20.

Is there a direct bus between Mayo Clinic and La Crosse?

Yes, there is a direct bus departing from Rochester and arriving at La Crosse. Services depart once daily, and operate every day. The journey takes approximately 1h 50m.

How far is it from Mayo Clinic to La Crosse?

The distance between Mayo Clinic and La Crosse is 76 miles. The road distance is 73 miles.

How do I travel from Mayo Clinic to La Crosse without a car?

The best way to get from Mayo Clinic to La Crosse without a car is to bus which takes 1h 58m and costs $28 - $40.

How long does it take to get from Mayo Clinic to La Crosse?

The bus from Rochester to La Crosse takes 1h 50m including transfers and departs once daily.

Where do I catch the Mayo Clinic to La Crosse bus from?

Mayo Clinic to La Crosse bus services, operated by Jefferson Lines, depart from Rochester station.

Where does the Mayo Clinic to La Crosse bus arrive?

Mayo Clinic to La Crosse bus services, operated by Jefferson Lines, arrive at La Crosse station.

Can I drive from Mayo Clinic to La Crosse?

Yes, the driving distance between Mayo Clinic to La Crosse is 73 miles. It takes approximately 1h 19m to drive from Mayo Clinic to La Crosse.

Where can I stay near La Crosse?

There are 45+ hotels available in La Crosse.

Mayo Clinic to La Crosse - 2 ways to travel via bus, and car

How to get fromMayo Clinic to La Crosse

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There are 2 ways to get from Mayo Clinic to La Crosse by bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from Rochester to La Crossebus Jefferson Lines 965
1h 58m
$28–40
Drive 72.6 mi
cheapest
1. Drive from Mayo Clinic to La Crossecar 72.6 mi
1h 19m
$14–20

Mayo Clinic to La Crosse by foot and bus

7Weekly Services

1h 58mAverage Duration

$28Cheapest Price

See schedules

Questions & Answers

Map of how to get from Mayo Clinic to La Crosse.

Launch map view

Distance: 75.6 mi
Duration: 1h 58m

What companies run services between Mayo Clinic, MN, USA and La Crosse, WI, USA?

Jefferson Lines operates a bus from Rochester to La Crosse once daily. Tickets cost $28–40 and the journey takes 1h 50m.

Operators

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