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How to get fromMayo Clinic to Madisonby bus, car, or plane

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There are 4 ways to get from Mayo Clinic to Madison by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Rochester, MN to UW-Madisonbus bus Minneapolis / ...
    4h 53m
    $55–80
  2. Drive 207.3 mi

    cheapest
    1. Drive from Mayo Clinic to Madisoncar car 207.3 mi
    3h 33m
    $38–55
  3. Fly from Rochester

    1. Fly from Rochester (RST) to Dane County Regional Airport-Truax Field (MSN)plane plane RST - MSN
    5h 48m
    $133–889
  4. Bus to Minneapolis–Saint Paul International Airport, fly

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Dane County Regional Airport-Truax Field (MSN)plane plane MSP - MSN
    4h 19m
    $127–552

Mayo Clinic to Madison by foot and bus

Calendar14Weekly Services
Duration4h 53mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

What companies run services between Mayo Clinic, MN, USA and Madison, WI, USA?

Jefferson Lines operates a bus from Rochester, MN to UW-Madison twice daily. Tickets cost $55–80 and the journey takes 4h 45m. Alternatively, United Airlines, American Airlines, and Delta fly from Rochester (RST) to Dane County Regional Airport-Truax Field (MSN) 5 times a day.

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