There are 4 ways to get from Mayo Clinic to Madison by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Rochester to Madisonbus Jefferson Lines 965
4h 23m$50–75Drive 207.3 mi
cheapest- Drive from Mayo Clinic to Madisoncar 207.3 mi
3h 33m$38–55Fly from Rochester
- Fly from Rochester (RST) to Dane County Regional Airport-Truax Field (MSN)plane RST - MSN
5h 48m$73–519Bus to Minneapolis–Saint Paul International Airport, fly
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Dane County Regional Airport-Truax Field (MSN)plane MSP - MSN
4h 21m$127–602
Mayo Clinic to Madison by foot and bus
Questions & Answers
The cheapest way to get from Mayo Clinic to Madison is to drive which costs $35 - $55 and takes 3h 33m.
The fastest way to get from Mayo Clinic to Madison is to drive which takes 3h 33m and costs $35 - $55.
Yes, there is a direct bus departing from Rochester and arriving at Madison. Services depart once daily, and operate every day. The journey takes approximately 4h 15m.
The distance between Mayo Clinic and Madison is 202 miles. The road distance is 208.5 miles.
The best way to get from Mayo Clinic to Madison without a car is to bus which takes 4h 23m and costs $50 - $75.
The bus from Rochester to Madison takes 4h 15m including transfers and departs once daily.
Mayo Clinic to Madison bus services, operated by Jefferson Lines, depart from Rochester station.
The best way to get from Mayo Clinic to Madison is to bus which takes 4h 23m and costs $50 - $75. Alternatively, you can fly, which costs $70 - $550 and takes 5h 48m.
Mayo Clinic to Madison bus services, operated by Jefferson Lines, arrive at Madison station.
Yes, the driving distance between Mayo Clinic to Madison is 208 miles. It takes approximately 3h 33m to drive from Mayo Clinic to Madison.
What companies run services between Mayo Clinic, MN, USA and Madison, WI, USA?
Jefferson Lines operates a bus from Rochester to Madison once daily. Tickets cost $50–75 and the journey takes 4h 15m. Alternatively, United Airlines, American Airlines, and Delta fly from Rochester (RST) to Dane County Regional Airport-Truax Field (MSN) every 4 hours.
- Website
- delta.com
Flights from Rochester to Dane County Regional Airport-Truax Field via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $70–480
Flights from Minneapolis–Saint Paul International Airport to Dane County Regional Airport-Truax Field
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $75–550
- Website
- aa.com
Flights from Rochester to Dane County Regional Airport-Truax Field via Chicago O'Hare
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $80–500
- Website
- united.com
Flights from Rochester to Dane County Regional Airport-Truax Field via Chicago O'Hare
- Ave. Duration
- 3h 29m
- When
- Every day
- Estimated price
- $80–500
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
More Questions & Answers
There are 136+ hotels available in Madison.