There are 4 ways to get from Mayo Clinic to Minneapolis by bus, tram, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, tram
best- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus Groome Transportation
- Take the tram from Terminal 1 Station to U.S. Bank Stadium Stationtram METRO Blue Line
1h 53m$52Drive 83.1 mi
cheapest- Drive from Mayo Clinic to Minneapoliscar 83.1 mi
1h 33m$15–21Fly
- Fly from Rochester (RST) to Minneapolis–Saint Paul International Airport (MSP)plane RST - MSP
2h 41m$48–399Bus
- Take the bus from Rochester to Minneapolisbus Jefferson Lines 966
2h 31m$30–45
Mayo Clinic to Minneapolis by foot and bus
Comparing Your Travel Options
The cheapest way to get from Mayo Clinic to Minneapolis is to drive which costs $14 - $21 and takes 1h 33m.
The fastest way to get from Mayo Clinic to Minneapolis is to drive which takes 1h 33m and costs $14 - $21.
Yes, there is a direct bus departing from Rochester and arriving at Minneapolis. Services depart once daily, and operate every day. The journey takes approximately 2h 25m.
The distance between Mayo Clinic and Minneapolis is 86 miles. The road distance is 83.6 miles.
The best way to get from Mayo Clinic to Minneapolis without a car is to bus and tram which takes 1h 53m and costs $52.
It takes approximately 1h 53m to get from Mayo Clinic to Minneapolis, including transfers.
Mayo Clinic to Minneapolis bus services, operated by Jefferson Lines, depart from Rochester station.
The best way to get from Mayo Clinic to Minneapolis is to fly which takes 2h 41m and costs $45 - $400. Alternatively, you can bus, which costs $30 - $45 and takes 2h 31m.
Mayo Clinic to Minneapolis bus services, operated by Jefferson Lines, arrive at Minneapolis station.
Yes, the driving distance between Mayo Clinic to Minneapolis is 84 miles. It takes approximately 1h 33m to drive from Mayo Clinic to Minneapolis.
What companies run services between Mayo Clinic, MN, USA and Minneapolis, MN, USA?
Delta flies from Rochester (RST) to Minneapolis–Saint Paul International Airport (MSP) 3 times a day. Alternatively, Jefferson Lines operates a bus from Rochester to Minneapolis once daily. Tickets cost $30–45 and the journey takes 2h 25m.
- Website
- delta.com
Flights from Rochester to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 53 min
- When
- Every day
- Estimated price
- $45–360
- Phone
- +1 612-373-3333
- Website
- Metro Transit
Tram from Terminal 1 Station to U.S. Bank Stadium Station
- Ave. Duration
- 20 min
- Frequency
- Every 15 minutes
- Estimated price
- $2
- Website
- Metro Transit
- Schedules at
- Metro Transit Schedules
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to Minneapolis
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
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