There are 6 ways to get from Mayo Clinic to Oakbrook Center by plane, bus, train, car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Rochester to Chicago O'Hare International Airport, line 332 bus
best- Fly from Rochester (RST) to Chicago O'Hare International Airport (ORD)plane RST - ORD
- Take the bus from Cargo Rd./Delta Cargo to Oak Brook Center / Macy'sbus
5h 7m$38–291Bus, train
- Take the bus from Rochester to Milwaukeebus Jefferson Lines 965
- Take the train from Milwaukee to Chicago Union Stationtrain Hiawatha Service / ...
10h 2m$119–179Drive 334.2 mi
- Drive from Mayo Clinic to Oakbrook Centercar 334.2 mi
5h 41m$58–83Bus to Minneapolis–Saint Paul International Airport, fly to Chicago Midway International Airport, line 322 bus
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago Midway International Airport (MDW)plane MSP - MDW
- Take the bus from 54th Ave CTA Station/Pink Line to Oak Brook Center / Macy'sbus
5h 46m$120–496Bus to Minneapolis–Saint Paul International Airport, fly to Chicago O'Hare International Airport
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago O'Hare International Airport (ORD)plane MSP - ORD
6h 7m$272–854Bus, subway
- Take the bus from Rochester to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departuresbus
- Take the subway from O'Hare to Forest Parksubway
10h 33m$81–132
Mayo Clinic to Oakbrook Center by foot, bus, train, and subway
Comparing Your Travel Options
The cheapest way to get from Mayo Clinic to Oakbrook Center is to drive which costs $55 - $85 and takes 5h 41m.
The fastest way to get from Mayo Clinic to Oakbrook Center is to fly and line 332 bus which takes 5h 7m and costs $35 - $300.
The distance between Mayo Clinic and Oakbrook Center is 295 miles. The road distance is 336.1 miles.
The best way to get from Mayo Clinic to Oakbrook Center without a car is to bus and train which takes 10h 2m and costs $110 - $180.
It takes approximately 5h 7m to get from Mayo Clinic to Oakbrook Center, including transfers.
Yes, the driving distance between Mayo Clinic to Oakbrook Center is 336 miles. It takes approximately 5h 41m to drive from Mayo Clinic to Oakbrook Center.
There are 244+ hotels available in Oakbrook Center.
What companies run services between Mayo Clinic, MN, USA and Oakbrook Center, IL, USA?
There is no direct connection from Mayo Clinic to Oakbrook Center. However, you can walk to Rochester, take the bus to Rochester, walk to Rochester (RST) airport, fly to Chicago O'Hare International Airport (ORD), walk to Cargo Rd./Delta Cargo, take the line 332 bus to Oak Brook Center / Macy's, then walk to Oakbrook Center. Alternatively, you can take a vehicle from Mayo Clinic to Oakbrook Center via Rochester, Milwaukee, Milwaukee, Chicago Union Station, LaSalle/Van Buren, 54th/Cermak, 54th Ave CTA Station/Pink Line, and Oak Brook Center / Macy's in around 10h 2m.
- Website
- delta.com
Flights from Rochester to Chicago O'Hare International Airport via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 29m
- When
- Every day
- Estimated price
- $40–270
Flights from Minneapolis–Saint Paul International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $65–440
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $45–310
- Website
- aa.com
Flights from Rochester to Chicago O'Hare International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $35–250
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $45–310
- Website
- southwest.com
Flights from Minneapolis–Saint Paul International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $65–440
Flights from Minneapolis–Saint Paul International Airport to Chicago Midway International Airport via St. Louis
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
- Website
- united.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $45–310
- Website
- suncountry.com
Flights from Minneapolis–Saint Paul International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 37m
- When
- Sunday to Friday
- Estimated price
- $45–310
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from O'Hare to Forest Park
- Ave. Duration
- 1h 23m
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
- Phone
- +1(847) 364-7223
- [email protected]
- Website
- Pace Bus
Bus from Cargo Rd./Delta Cargo to Oak Brook Center / Macy's
- Ave. Duration
- 45 min
- Frequency
- Every 4 hours
- Estimated price
- $2–4
- Website
- Pace Bus
- Schedules at
- Pace Bus Routes, Schedules and Maps
- Adult
- $2–4
Bus from 54th Ave CTA Station/Pink Line to Oak Brook Center / Macy's
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–3
- Website
- Pace Bus
- Schedules at
- Pace Bus Routes, Schedules and Maps
- Adult
- $2–3
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to Milwaukee
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide












