There are 5 ways to get from Mayo Clinic to Oshkosh by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Rochester, MN to University of Wisconsin - La Crossebus
- Take the bus from UW-La Crosse to Waupaca Mobilbus
- Take the bus from Waupaca to UW–Oshkoshbus
9h 18m$75–91Drive 217.2 mi
cheapest- Drive from Mayo Clinic to Oshkoshcar 217.2 mi
4h 19m$40–58Fly from Rochester
- Fly from Rochester (RST) to Appleton International Airport (ATW)plane RST - ATW
5h 45m$131–692Bus via Milwaukee
- Take the bus from Rochester, MN to Milwaukee, WI - Amtrakbus Minneapolis / ...
- Take the bus from Milwaukee to UW–Oshkoshbus Milwaukee
9h 23m$94–124Bus to Minneapolis–Saint Paul International Airport, fly
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Appleton International Airport (ATW)plane MSP - ATW
3h 56m$185–755
Mayo Clinic to Oshkosh by foot and bus
Questions & Answers
The cheapest way to get from Mayo Clinic to Oshkosh is to drive which costs $35 - $60 and takes 4h 19m.
The fastest way to get from Mayo Clinic to Oshkosh is to bus and fly which takes 3h 56m and costs $180 - $800.
No, there is no direct bus from Mayo Clinic to Oshkosh. However, there are services departing from Rochester, MN and arriving at UW–Oshkosh via UW-La Crosse and Waupaca. The journey, including transfers, takes approximately 9h 18m.
The distance between Mayo Clinic and Oshkosh is 284 miles. The road distance is 218.5 miles.
The best way to get from Mayo Clinic to Oshkosh without a car is to bus which takes 9h 18m and costs $70 - $95.
It takes approximately 9h 18m to get from Mayo Clinic to Oshkosh, including transfers.
Mayo Clinic to Oshkosh bus services, operated by Jefferson Lines, depart from Rochester, MN station.
The best way to get from Mayo Clinic to Oshkosh is to bus which takes 9h 18m and costs $70 - $95. Alternatively, you can fly, which costs $130 - $700 and takes 5h 45m.
Mayo Clinic to Oshkosh bus services, operated by Jefferson Lines, arrive at University of Wisconsin - La Crosse station.
Yes, the driving distance between Mayo Clinic to Oshkosh is 218 miles. It takes approximately 4h 19m to drive from Mayo Clinic to Oshkosh.
What companies run services between Mayo Clinic, MN, USA and Oshkosh, WI, USA?
You can take a vehicle from Mayo Clinic to UW–Oshkosh via Rochester, MN, University of Wisconsin - La Crosse, UW-La Crosse, and Waupaca in around 9h 18m. Alternatively, Delta, United Airlines, and American Airlines fly from Rochester (RST) to Appleton International Airport (ATW) every 3 hours.
- Website
- delta.com
Flights from Rochester to Appleton International Airport via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $90–600
Flights from Rochester to Appleton International Airport via Minneapolis–Saint Paul International Airport, Detroit
- Ave. Duration
- 7h 58m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–850
Flights from Minneapolis–Saint Paul International Airport to Appleton International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $95–650
- Website
- united.com
Flights from Rochester to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $100–650
- Website
- aa.com
Flights from Rochester to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $100–650
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester, MN to University of Wisconsin - La Crosse
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Bus from Rochester, MN to Milwaukee, WI - Amtrak
- Ave. Duration
- 6h 25m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Book at
- https://www.jeffersonlines.com
- Adult
- $70–110
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from UW-La Crosse to Waupaca Mobil
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $29–33
- Schedules at
- golamers.com
Bus from Waupaca to UW–Oshkosh
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $17–19
- Schedules at
- golamers.com
Bus from Milwaukee to UW–Oshkosh
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $20–23
- Schedules at
- golamers.com
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
More Questions & Answers
There are 60+ hotels available in Oshkosh.




