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How to get fromMayo Clinic to Ottawaby bus, plane, bus (Flixbus), train, or car

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There are 7 ways to get from Mayo Clinic to Ottawa by bus, plane, bus (Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Minneapolis–Saint Paul International Airport, fly to Ottawa Macdonald-Cartier International Airport

    best
    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Ottawa Macdonald-Cartier International Airport (YOW)plane plane MSP - YOW
    8h 23m
    $226–876

  2. Fly Rochester to Ottawa Macdonald-Cartier International Airport

    cheapest
    1. Fly from Rochester (RST) to Ottawa Macdonald-Cartier International Airport (YOW)plane plane RST - YOW
    9h 6m
    $127–707

  3. Bus

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Ottawabus bus
    28h 36m
    $294–446

  4. Bus, train via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo to Toronto Union Stationtrain train
    5. Take the train from Toronto Union Station to Ottawatrain train
    31h 52m
    $667–1,400

  5. Drive  1,651.1 km

    1. Drive from Mayo Clinic to Ottawacar car 1,651.1 km
    20h 36m
    $300–433

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Montréal–Pierre Elliott Trudeau International Airport, train

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Montréal–Pierre Elliott Trudeau International Airport (YUL)plane plane MSP - YUL
    3. Take the train from Dorval to Ottawatrain train
    8h 39m
    $610–2,215

  7. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo to Toronto Union Stationtrain train
    5. Take the train from Toronto Union Station to Ottawatrain train
    32h 44m
    $901–1,756

Mayo Clinic to Ottawa by foot and bus

Calendar4Weekly Services
Duration28h 36mAverage Duration
Ticket$294Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mayo Clinic to Ottawa.ExpandLaunch map view
  • Distance: 1,513.1 km
  • Duration: 8h 23m

What companies run services between Mayo Clinic, MN, USA and Ottawa, ON, Canada?

You can take a vehicle from Mayo Clinic to Ottawa via Rochester, Milwaukee, Milwaukee Intermodal Station, and Detroit Bus Station in around 28h 36m. Alternatively, American Airlines, United Airlines, and three other airlines fly from Rochester (RST) to Ottawa Macdonald-Cartier International Airport (YOW) every 4 hours.

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Train operators
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