There are 7 ways to get from Mayo Clinic to Ottawa by plane, bus (Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Rochester to Ottawa Macdonald-Cartier International Airport
best- Fly from Rochester (RST) to Ottawa Macdonald-Cartier International Airport (YOW)plane RST - YOW
9h 2m$127–707Bus
- Take the bus from Rochester to Milwaukeebus
- Take the bus from Milwaukee Intermodal Station to Detroit Bus Stationbus
- Take the bus from Detroit Bus Station to Ottawabus
27h 43m$288–445Bus, train via Madison
- Take the bus from Rochester to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain
- Take the train from Buffalo to Toronto Union Stationtrain
- Take the train from Toronto Union Station to Ottawatrain
31h 44m$656–1,399Drive 1,651.2 km
- Drive from Mayo Clinic to Ottawacar 1,651.2 km
20h 36m$329–475Bus to Minneapolis–Saint Paul International Airport, fly to Ottawa Macdonald-Cartier International Airport
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Ottawa Macdonald-Cartier International Airport (YOW)plane MSP - YOW
8h 23m$215–825Bus to Minneapolis–Saint Paul International Airport, fly to Montréal–Pierre Elliott Trudeau International Airport, train
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Montréal–Pierre Elliott Trudeau International Airport (YUL)plane MSP - YUL
- Take the train from Dorval to Ottawatrain
8h 41m$609–2,214Bus, train
- Take the bus from Rochester to St. Paulbus
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain
- Take the train from Buffalo to Toronto Union Stationtrain
- Take the train from Toronto Union Station to Ottawatrain
32h 36m$890–1,755
Mayo Clinic to Ottawa by foot and bus
Comparing Your Travel Options
The cheapest way to get from Mayo Clinic to Ottawa is to fly which costs $120 - $750 and takes 9h 2m.
The fastest way to get from Mayo Clinic to Ottawa is to bus and fly which takes 8h 23m and costs $210 - $850.
No, there is no direct bus from Mayo Clinic to Ottawa. However, there are services departing from Rochester and arriving at Ottawa via Milwaukee Intermodal Station and Detroit Bus Station. The journey, including transfers, takes approximately 27h 43m.
The distance between Mayo Clinic and Ottawa is 1365 km. The road distance is 1651.2 km.
The best way to get from Mayo Clinic to Ottawa without a car is to bus which takes 27h 43m and costs $280 - $450.
It takes approximately 9h 2m to get from Mayo Clinic to Ottawa, including transfers.
Mayo Clinic to Ottawa bus services, operated by Jefferson Lines, depart from Rochester station.
The best way to get from Mayo Clinic to Ottawa is to fly which takes 9h 2m and costs $120 - $750. Alternatively, you can bus, which costs $280 - $450 and takes 27h 43m.
Mayo Clinic to Ottawa bus services, operated by Jefferson Lines, arrive at Milwaukee station.
Yes, the driving distance between Mayo Clinic to Ottawa is 1651 km. It takes approximately 20h 36m to drive from Mayo Clinic to Ottawa.
What companies run services between Mayo Clinic, MN, USA and Ottawa, ON, Canada?
American Airlines, United Airlines, and four other airlines fly from Rochester (RST) to Ottawa Macdonald-Cartier International Airport (YOW) every 4 hours. Alternatively, you can take a vehicle from Mayo Clinic to Ottawa via Rochester, Milwaukee, Milwaukee Intermodal Station, and Detroit Bus Station in around 27h 43m.
- Website
- aircanada.com
Flights from Rochester to Ottawa Macdonald-Cartier International Airport via Chicago O'Hare
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $120–650
Flights from Rochester to Ottawa Macdonald-Cartier International Airport via Minneapolis–Saint Paul International Airport, Montréal–Pierre Elliott Trudeau International Airport
- Ave. Duration
- 7h 24m
- When
- Monday, Thursday, and Saturday
- Estimated price
- $130–700
Flights from Rochester to Ottawa Macdonald-Cartier International Airport via Minneapolis–Saint Paul International Airport, Toronto
- Ave. Duration
- 8h 51m
- When
- Every day
- Estimated price
- $120–650
Flights from Minneapolis–Saint Paul International Airport to Ottawa Macdonald-Cartier International Airport via Toronto
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $140–750
Flights from Minneapolis–Saint Paul International Airport to Ottawa Macdonald-Cartier International Airport via Chicago O'Hare
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $150–750
Flights from Minneapolis–Saint Paul International Airport to Ottawa Macdonald-Cartier International Airport via Montréal–Pierre Elliott Trudeau International Airport
- Ave. Duration
- 5h 37m
- When
- Monday, Thursday, and Saturday
- Estimated price
- $150–800
Flights from Minneapolis–Saint Paul International Airport to Montréal–Pierre Elliott Trudeau International Airport
- Ave. Duration
- 2h 32m
- When
- Monday, Thursday, and Saturday
- Estimated price
- $140–750
Flights from Minneapolis–Saint Paul International Airport to Montréal–Pierre Elliott Trudeau International Airport via Toronto
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $150–750
- Website
- united.com
Flights from Rochester to Ottawa Macdonald-Cartier International Airport via Chicago O'Hare
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $120–650
Flights from Rochester to Ottawa Macdonald-Cartier International Airport via Minneapolis–Saint Paul International Airport, Toronto
- Ave. Duration
- 9h 7m
- When
- Every day
- Estimated price
- $120–650
Flights from Minneapolis–Saint Paul International Airport to Ottawa Macdonald-Cartier International Airport via Toronto
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $140–750
Flights from Minneapolis–Saint Paul International Airport to Ottawa Macdonald-Cartier International Airport via Chicago O'Hare
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $150–750
Flights from Minneapolis–Saint Paul International Airport to Ottawa Macdonald-Cartier International Airport via Washington Dulles
- Ave. Duration
- 6h 51m
- When
- Saturday
- Estimated price
- $190–900
Flights from Minneapolis–Saint Paul International Airport to Montréal–Pierre Elliott Trudeau International Airport
- Ave. Duration
- 2h 32m
- When
- Monday, Thursday, and Saturday
- Estimated price
- $140–750
- Website
- delta.com
Flights from Rochester to Ottawa Macdonald-Cartier International Airport via Minneapolis–Saint Paul International Airport, Toronto
- Ave. Duration
- 12h 21m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Minneapolis–Saint Paul International Airport to Ottawa Macdonald-Cartier International Airport via Toronto
- Ave. Duration
- 8h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Minneapolis–Saint Paul International Airport to Montréal–Pierre Elliott Trudeau International Airport
- Ave. Duration
- 2h 37m
- When
- Every day
- Estimated price
- $140–750
Flights from Minneapolis–Saint Paul International Airport to Montréal–Pierre Elliott Trudeau International Airport via Detroit
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $150–750
- Website
- westjet.com
Flights from Rochester to Ottawa Macdonald-Cartier International Airport via Minneapolis–Saint Paul International Airport, Toronto
- Ave. Duration
- 12h 21m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Minneapolis–Saint Paul International Airport to Ottawa Macdonald-Cartier International Airport via Toronto
- Ave. Duration
- 8h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Minneapolis–Saint Paul International Airport to Montréal–Pierre Elliott Trudeau International Airport
- Ave. Duration
- 2h 37m
- When
- Every day
- Estimated price
- $140–750
Flights from Minneapolis–Saint Paul International Airport to Montréal–Pierre Elliott Trudeau International Airport via Detroit
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $150–750
- Website
- flyporter.com
Flights from Rochester to Ottawa Macdonald-Cartier International Airport via Chicago O'Hare, Toronto
- Ave. Duration
- 10h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $290–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $400–650
- Website
- Amtrak
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 32m
- Frequency
- 3 times a day
- Estimated price
- $310–490
- Website
- Amtrak
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $400–650
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Buffalo to Toronto Union Station
- Ave. Duration
- 4h 14m
- Frequency
- Once daily
- Estimated price
- $40–240
- Website
- VIA Rail
- Escape
- $40–130
- Business
- $85–230
- Business Plus
- $100–240
- Economy
- $45–140
- Economy Plus
- $50–150
Train from Toronto Union Station to Ottawa
- Ave. Duration
- 4h 49m
- Frequency
- Every 4 hours
- Estimated price
- $100–320
- Website
- VIA Rail
- Escape
- $100–250
- Business
- $150–310
- Business Plus
- $160–320
- Economy
- $110–260
- Economy Plus
- $120–270
Train from Dorval to Ottawa
- Ave. Duration
- 1h 32m
- Frequency
- 5 times a day
- Estimated price
- $35–240
- Website
- VIA Rail
- Escape
- $35–120
- Business
- $85–220
- Business Plus
- $100–240
- Economy
- $40–130
- Economy Plus
- $45–140
Train from Buffalo to Toronto Union Station
- Ave. Duration
- 4h 14m
- Frequency
- Once daily
- Estimated price
- $40–240
- Website
- VIA Rail
- Escape
- $40–130
- Business
- $85–230
- Business Plus
- $100–240
- Economy
- $45–140
- Economy Plus
- $50–150
Train from Toronto Union Station to Ottawa
- Ave. Duration
- 4h 49m
- Frequency
- Every 4 hours
- Estimated price
- $100–320
- Website
- VIA Rail
- Escape
- $100–250
- Business
- $150–310
- Business Plus
- $160–320
- Economy
- $110–260
- Economy Plus
- $120–270
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester to Milwaukee
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- Jefferson Lines
- Adult
- $95–140
Bus from Rochester to Madison
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $75–110
- Book at
- Jefferson Lines
- Adult
- $75–110
Bus from Rochester to St. Paul
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $40–55
- Book at
- Jefferson Lines
- Adult
- $40–55
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Detroit Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- 4 times a week
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
Bus from Detroit Bus Station to Ottawa
- Ave. Duration
- 12h 25m
- Frequency
- 3 times a week
- Estimated price
- $110–180
- Schedules at
- Flixbus USA
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $35–80
- Schedules at
- Rockland Coaches
- Adult
- $35–80
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $60–70
- Website
- Groome Transportation - Rochester - MSP
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $60–70
- Website
- Groome Transportation - Rochester - MSP
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