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How to get fromMayo Clinic to Pennsylvaniaby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 13 ways to get from Mayo Clinic to Pennsylvania by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Wilkes-Barre/Scranton International Airport

    best
    1. Fly from Rochester (RST) to Wilkes-Barre/Scranton International Airport (AVP)plane plane RST - AVP
    5h 56m
    $141–587

  2. Fly Rochester to Erie International Airport

    cheapest
    1. Fly from Rochester (RST) to Erie International Airport (ERI)plane plane RST - ERI
    12h 13m
    $73–419

  3. Bus

    1. Take the bus from Rochester, MN to Milwaukee, WI - Amtrakbus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Newark Penn Stationbus bus
    4. Take the bus from Newark Penn Station to Philadelphia Bus Stationbus bus
    29h 19m
    $229–380

  4. Bus, train via Milwaukee

    1. Take the bus from Rochester, MN to Milwaukee, WI - Amtrakbus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Rockville Amtraktrain train
    4. Take the train from Washington Union Station to 30th Street Stationtrain train
    29h 28m
    $386–757

  5. Drive 1,103.9 mi

    1. Drive from Mayo Clinic to Philadelphiacar car 1,103.9 mi
    18h 7m
    $202–291

  6. Fly Rochester to Philadelphia International Airport

    1. Fly from Rochester (RST) to Philadelphia International Airport (PHL)plane plane RST - PHL
    6h 29m
    $124–640

  7. Fly Rochester to Pittsburgh International Airport

    1. Fly from Rochester (RST) to Pittsburgh International Airport (PIT)plane plane RST - PIT
    6h 44m
    $86–477

  8. Bus to Minneapolis–Saint Paul International Airport, fly to Philadelphia International Airport

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Philadelphia International Airport (PHL)plane plane MSP - PHL
    5h 40m
    $233–903

  9. Bus to Minneapolis–Saint Paul International Airport, fly to Pittsburgh International Airport

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Pittsburgh International Airport (PIT)plane plane MSP - PIT
    5h 55m
    $550–1,050

  10. Bus to Minneapolis–Saint Paul International Airport, fly to Cleveland-Hopkins International Airport, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Cleveland-Hopkins International Airport (CLE)plane plane MSP - CLE
    3. Take the bus from Cleveland Bus Station to Eriebus bus
    7h 28m
    $620–1,088

  11. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Rockville Amtraktrain train
    4. Take the train from Washington Union Station to 30th Street Stationtrain train
    30h 21m
    $444–905

  12. Bus via Baltimore

    1. Take the bus from Rochester, MN to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus bus
    4. Take the bus from Baltimore Greyhound Garage to Philadelphia Bus Stationbus bus
    34h 23m
    $220–414

  13. Bus, train #2

    1. Take the bus from Rochester, MN to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to 30th Street Stationtrain train
    36h 42m
    $427–842

Mayo Clinic to Pennsylvania by foot and bus

Calendar16Weekly Services
Duration29h 19mAverage Duration
Ticket$229Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Pennsylvania.ExpandLaunch map view
  • Distance: 886 mi
  • Duration: 5h 56m

What companies run services between Mayo Clinic, MN, USA and Pennsylvania, USA?

United Airlines and American Airlines fly from Rochester (RST) to Wilkes-Barre/Scranton International Airport (AVP) 4 times a day. Alternatively, you can take a vehicle from Mayo Clinic to Philadelphia Bus Station via Rochester, MN, Milwaukee Intermodal Station, Chicago Bus Station, and Newark Penn Station in around 29h 19m.

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