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How to get fromMayo Clinic to Peoriaby plane, bus, train, or car

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There are 5 ways to get from Mayo Clinic to Peoria by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Peoria International Airport

    best
    1. Fly from Rochester (RST) to Peoria International Airport (PIA)plane plane RST - PIA
    6h 29m
    $52–368

  2. Bus, train

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg Amtrak Station to Peoria Amtrak Stationbus bus
    13h 53m
    $161–283

  3. Drive 325.8 mi

    1. Drive from Mayo Clinic to Peoriacar car 325.8 mi
    6h 35m
    $60–86

  4. Bus to Minneapolis–Saint Paul International Airport, fly to The Eastern Iowa Airport, drive

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to The Eastern Iowa Airport (CID)plane plane MSP - CID
    3. Drive from Cedar-Rapids-Airport-CID to Peoriacar car
    6h 30m
    $125–435

  5. Bus

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departuresbus bus
    3. Take the bus from Multi-Modal Facility to Peoriabus bus
    14h 17m
    $125–192

Mayo Clinic to Peoria by foot, bus, and train

Calendar7Weekly Services
Duration13h 53mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Peoria.ExpandLaunch map view
  • Distance: 281.6 mi
  • Duration: 6h 29m

What companies run services between Mayo Clinic, MN, USA and Peoria, IL, USA?

American Airlines and United Airlines fly from Rochester (RST) to Peoria International Airport (PIA) twice daily. Alternatively, you can take a vehicle from Mayo Clinic to Peoria via Rochester, Madison, 250 N. Lake St - Madison UW Campus, O'Hare International Airport - Terminal 2 Departures, O'Hare, Rosemont, Rosemont CTA Station, O'Hare MMF Bay 8, and Multi-Modal Facility in around 14h 17m.

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