Rome2Rio

How to get fromMayo Clinic to Rochester Airport (ROC)by plane, bus, train, bus (Greyhound, Flixbus), bus (Flixbus, Greyhound), or car

Find Transport to Rochester Airport (ROC)

See all options

There are 8 ways to get from Mayo Clinic to Rochester Airport (ROC) by plane, bus, train, bus (Greyhound, Flixbus), bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Rochester

    best
    1. Fly from Rochester (RST) to Rochester (ROC)plane plane RST - ROC
    7h 54m
    $161–887

  2. Bus to Minneapolis–Saint Paul International Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Buffalo Niagara International Airport (BUF)plane plane MSP - BUF
    3. Take the bus from Buffalo Niagara International Airport to Rochester Bus Stopbus bus
    6h 35m
    $218–889

  3. Bus, train via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Rochestertrain train
    21h 37m
    $419–657

  4. Bus

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago to Clevelandbus bus
    4. Take the bus from Cleveland to Buffalobus bus
    5. Take the bus from Buffalo to Rochester Bus Stopbus bus
    22h 38m
    $162–305

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Rochester

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Rochester (ROC)plane plane MSP - ROC
    6h 25m
    $250–1,150

  6. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Rochestertrain train
    22h 48m
    $588–912

  7. Bus via Detroit

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Torontobus bus
    4. Take the bus from Toronto to Rochester Bus Stopbus bus
    28h 6m
    $206–319

  8. Drive  942.7 mi

    1. Drive from Mayo Clinic to Rochester Airport (ROC)car car 942.7 mi
    15h 51m
    $162–233

Rochester (RST) to Rochester (ROC) flights

Calendar35Weekly Planes
Duration7h 50mAverage Duration
Ticket$161Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Mayo Clinic to Rochester Airport (ROC).ExpandLaunch map view
  • Distance: 752.3 mi
  • Duration: 7h 54m

What companies run services between Mayo Clinic, MN, USA and Rochester Airport (ROC), USA?

American Airlines and Delta fly from Rochester (RST) to Rochester (ROC) 5 times a day. Alternatively, you can take a vehicle from Mayo Clinic to Rochester Airport (ROC) via Rochester, Milwaukee, Milwaukee Intermodal Station, Chicago, Cleveland, Buffalo, and Rochester Bus Stop in around 22h 38m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There