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How to get fromMayo Clinic to Saint Augustineby plane, bus, bus (Greyhound, Flixbus), train, taxi, or car

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There are 8 ways to get from Mayo Clinic to Saint Augustine by plane, bus, bus (Greyhound, Flixbus), train, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Jacksonville, bus

    best
    1. Fly from Rochester (RST) to Jacksonville (JAX)plane plane RST - JAX
    2. Take the bus from JRTC - Express Select to St. Johns Adminsistrationbus bus
    10h 57m
    $124–607

  2. Bus

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    5. Take the bus from JRTC - Express Select to St. Johns Adminsistrationbus bus
    35h 51m
    $250–469

  3. Bus, train, taxi

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Jacksonvilletrain train
    4. Take the taxi from Jacksonville to Saint Augustinetaxi taxi
    46h 57m
    $769–1,549

  4. Drive 1,333.8 mi

    1. Drive from Mayo Clinic to Saint Augustinecar car 1,333.8 mi
    24h 34m
    $244–352

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Jacksonville, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Jacksonville (JAX)plane plane MSP - JAX
    3. Take the bus from JRTC - Express Select to St. Johns Adminsistrationbus bus
    9h 27m
    $203–720

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Orlando, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Orlando (MCO)plane plane MSP - MCO
    3. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    11h 13m
    $323–1,254

  7. Drive to The Eastern Iowa Airport, fly to Orlando Sanford, drive

    1. Drive from Mayo Clinic to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Orlando Sanford (SFB)plane plane CID - SFB
    3. Drive from Orlando-Sanford-Airport-SFB to Saint Augustinecar car
    7h 48m
    $248–1,020

  8. Bus, train

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Jacksonvilletrain train
    4. Take the bus from JRTC - Express Select to St. Johns Adminsistrationbus bus
    2d
    $593–1,254

Rochester (RST) to Jacksonville (JAX) flights

Calendar22Weekly Planes
Duration6h 49mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Saint Augustine.ExpandLaunch map view
  • Distance: 1,169.6 mi
  • Duration: 10h 57m

What companies run services between Mayo Clinic, MN, USA and Saint Augustine, FL, USA?

You can take a vehicle from Mayo Clinic to Saint Augustine via Rochester, Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, Atlanta Bus Station, Jacksonville, JRTC - Express Select, and St. Johns Adminsistration in around 35h 51m.

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