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How to get fromMayo Clinic to Santa Feby plane, shuttle, bus, train, bus (Greyhound), or car

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There are 10 ways to get from Mayo Clinic to Santa Fe by plane, shuttle, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Santa Fe Municipal Airport

    best
    1. Fly from Rochester (RST) to Santa Fe Municipal Airport (SAF)plane plane RST - SAF
    9h 58m
    $117–533

  2. Shuttle, bus, train

    1. Take a shuttle bus from Rochester to Owatonna, MNshuttle bus
    2. Take the bus from Owatonna to Kansas Citybus bus
    3. Take the train from Kansas City to Lamy Stationtrain train
    29h 7m
    $362–726

  3. Bus

    1. Take the bus from Rochester to Minneapolisbus bus
    2. Take the bus from Minneapolis to Tulsabus bus
    3. Take the bus from Tulsa Bus Station to Albuquerque Bus Stationbus bus
    4. Take the bus from Albuquerque to Santa Febus bus
    36h 9m
    $310–486

  4. Drive 1,152.6 mi

    1. Drive from Mayo Clinic to Santa Fecar car 1,152.6 mi
    19h 25m
    $211–304

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Santa Fe Municipal Airport

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Santa Fe Municipal Airport (SAF)plane plane MSP - SAF
    7h
    $171–626

  6. Drive to Fort Dodge Municipal Airport, fly to Santa Fe Municipal Airport

    1. Drive from Mayo Clinic to Fort Dodge Municipal Airport (FOD)car car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Santa Fe Municipal Airport (SAF)plane plane FOD - SAF
    14h 18m
    $138–502

  7. Fly Rochester to Albuquerque International Airport, train

    1. Fly from Rochester (RST) to Albuquerque International Airport (ABQ)plane plane RST - ABQ
    2. Take the train from Downtown Albuquerque Rail Runner Station to Santa Fe Depot Rail Runner Stationtrain train
    11h 33m
    $137–697

  8. Bus to Minneapolis–Saint Paul International Airport, fly to Albuquerque International Airport, train

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Albuquerque International Airport (ABQ)plane plane MSP - ABQ
    3. Take the train from Downtown Albuquerque Rail Runner Station to Santa Fe Depot Rail Runner Stationtrain train
    8h 51m
    $196–810

  9. Bus, train via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Lamy Stationtrain train
    35h 42m
    $476–993

  10. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Lamy Stationtrain train
    36h 41m
    $545–1,168

Mayo Clinic to Santa Fe by foot, bus, and train

Calendar7Weekly Services
Duration35h 42mAverage Duration
Ticket$476Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Santa Fe.ExpandLaunch map view
  • Distance: 938.5 mi
  • Duration: 9h 58m

What companies run services between Mayo Clinic, MN, USA and Santa Fe, NM, USA?

American Airlines, United Airlines, and Delta fly from Rochester (RST) to Santa Fe Municipal Airport (SAF) every 4 hours. Alternatively, you can take a vehicle from Mayo Clinic to Sandoval @ Water IB via Rochester, Minneapolis, Tulsa Bus Station, Albuquerque Bus Station, Albuquerque, and Santa Fe Place in around 36h 9m.

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