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How to get fromMayo Clinic to Springfieldby plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 8 ways to get from Mayo Clinic to Springfield by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Bradley International Airport

    best
    1. Fly from Rochester (RST) to Bradley International Airport (BDL)plane plane RST - BDL
    9h 17m
    $131–702

  2. Bus, train via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Springfieldtrain train
    29h 18m
    $580–934

  3. Bus

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to New York Midtownbus bus
    4. Take the bus from New York Midtown to Springfield Union Stationbus bus
    33h 13m
    $254–384

  4. Drive  1,244.1 mi

    1. Drive from Mayo Clinic to Springfieldcar car 1,244.1 mi
    21h 3m
    $227–328

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Bradley International Airport

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Bradley International Airport (BDL)plane plane MSP - BDL
    7h 2m
    $210–865

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Boston Logan Airport, train

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Boston Logan Airport (BOS)plane plane MSP - BOS
    3. Take the train from Boston to Springfieldtrain train
    9h 12m
    $509–1,144

  7. Bus to Minneapolis–Saint Paul International Airport, fly to Laguardia Airport, train

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Laguardia Airport (LGA)plane plane MSP - LGA
    3. Take the train from 125th Street - Harlem to New Haventrain train
    4. Take the train from New Haven to Springfieldtrain train
    10h 32m
    $311–791

  8. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Springfieldtrain train
    30h 29m
    $749–1,189

Mayo Clinic to Springfield by foot, bus, and train

Calendar7Weekly Services
Duration29h 18mAverage Duration
Ticket$580Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mayo Clinic to Springfield.ExpandLaunch map view
  • Distance: 1,037.3 mi
  • Duration: 9h 17m

What companies run services between Mayo Clinic, MN, USA and Springfield, MA, USA?

American Airlines and Delta fly from Rochester (RST) to Bradley International Airport (BDL) every 4 hours. Alternatively, you can take a vehicle from Mayo Clinic to Springfield Union Station via Rochester, Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and New York Midtown in around 33h 13m.

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