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How to get fromMayo Clinic to Springfieldby plane, bus, or car

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There are 4 ways to get from Mayo Clinic to Springfield by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Rochester

    best
    1. Fly from Rochester (RST) to Springfield-Branson National Airport (SGF)plane plane RST - SGF
    7h 51m
    $160–739

  2. Drive 543.8 mi

    cheapest
    1. Drive from Mayo Clinic to Springfieldcar car 543.8 mi
    9h 53m
    $100–144

  3. Bus

    1. Take the bus from Rochester to Albert Leabus bus
    2. Take the bus from Albert Lea to Kansas Citybus bus
    3. Take the bus from Kansas City to Springfieldbus bus
    14h 23m

  4. Bus to Minneapolis–Saint Paul International Airport, fly

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Springfield-Branson National Airport (SGF)plane plane MSP - SGF
    7h 20m
    $161–540

Rochester (RST) to Springfield-Branson National Airport (SGF) flights

Calendar8Weekly Planes
Duration6h 23mAverage Duration
Ticket$144Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Springfield.ExpandLaunch map view
  • Distance: 480 mi
  • Duration: 7h 51m

What companies run services between Mayo Clinic, MN, USA and Springfield, MO, USA?

American Airlines and United Airlines fly from Rochester (RST) to Springfield-Branson National Airport (SGF) once daily. Alternatively, you can take a vehicle from Mayo Clinic to Springfield via Rochester, Albert Lea, and Kansas City in around 14h 23m.

Airlines
Bus operators

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