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How to get fromMayo Clinic to Toledoby bus (Amtrak), bus, train, car, plane, or bus (Flixbus, Greyhound)

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There are 10 ways to get from Mayo Clinic to Toledo by bus (Amtrak), bus, train, car, plane, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Chicago

    best
    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Toledobus bus
    13h 55m

  2. Drive  585.5 mi

    cheapest
    1. Drive from Mayo Clinic to Toledocar car 585.5 mi
    9h 46m
    $104–150

  3. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Toledotrain train
    15h 7m
    $369–589

  4. Fly Rochester to Detroit, bus

    1. Fly from Rochester (RST) to Detroit (DTW)plane plane RST - DTW
    2. Take the bus from Dearborn to Toledobus bus
    8h 34m

  5. Bus, train via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Toledotrain train
    13h 56m
    $200–334

  6. Bus

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from Madison to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Toledo Bus Stopbus bus
    15h 21m
    $116–194

  7. Bus to Minneapolis–Saint Paul International Airport, fly to Detroit, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Detroit (DTW)plane plane MSP - DTW
    3. Take the bus from Dearborn to Toledobus bus
    7h 19m

  8. Bus to Minneapolis–Saint Paul International Airport, fly to Fort Wayne International Airport, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Fort Wayne International Airport (FWA)plane plane MSP - FWA
    3. Take the bus from Fort Wayne to Toledobus bus
    6h 53m
    $167–546

  9. Bus to Minneapolis–Saint Paul International Airport, fly to Cleveland-Hopkins International Airport, train

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Cleveland-Hopkins International Airport (CLE)plane plane MSP - CLE
    3. Take the train from Cleveland Amtrak to Toledotrain train
    8h 24m
    $908–1,148

  10. Fly Rochester to Chicago O'Hare International Airport, train

    1. Fly from Rochester (RST) to Chicago O'Hare International Airport (ORD)plane plane RST - ORD
    2. Take the train from Chicago Union Station to Toledotrain train
    8h 55m
    $161–495

Rochester (RST) to Detroit (DTW) flights

Calendar60Weekly Planes
Duration6h 30mAverage Duration
Ticket$87Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Mayo Clinic to Toledo.ExpandLaunch map view
  • Distance: 608 mi
  • Duration: 13h 55m

What companies run services between Mayo Clinic, MN, USA and Toledo, OH, USA?

You can take a vehicle from Mayo Clinic to Toledo via Rochester, Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 13h 55m.

Airlines
Train operators
Bus operators

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