There are 10 ways to get from Mayo Clinic to Toledo by bus (Amtrak), bus, train, car, plane, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Rochester, MN to UW-Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Union Station to Toledobus
14h 17m$169–259Drive 585.6 mi
cheapest- Drive from Mayo Clinic to Toledocar 585.6 mi
9h 46m$107–155Bus, train
- Take the bus from Rochester to St. Paulbus
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Toledotrain
14h 54m$234–469Fly Rochester to Detroit, bus
- Fly from Rochester (RST) to Detroit (DTW)plane RST - DTW
- Take the bus from Dearborn to Toledobus
8h 54m$178–866Bus, train via Madison
- Take the bus from Rochester, MN to UW-Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to Toledotrain
14h 18m$159–299Bus via Lake Delton
- Take the bus from Rochester, MN to Wisconsin Dellsbus
- Take the bus from Wisconsin Dells to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Toledo Bus Stopbus
14h 33m$112–205Bus to Minneapolis–Saint Paul International Airport, fly to Detroit, bus
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Detroit (DTW)plane MSP - DTW
- Take the bus from Dearborn to Toledobus
7h 24m$546–1,287Bus to Minneapolis–Saint Paul International Airport, fly to Fort Wayne International Airport, bus
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Fort Wayne International Airport (FWA)plane MSP - FWA
- Take the bus from Fort Wayne, IN to Toledobus
6h 55m$159–509Bus to Minneapolis–Saint Paul International Airport, fly to Cleveland-Hopkins International Airport, train
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Cleveland-Hopkins International Airport (CLE)plane MSP - CLE
- Take the train from Cleveland Amtrak to Toledotrain
8h 22m$638–1,123Bus to Minneapolis–Saint Paul International Airport, fly to John Glenn Columbus International Airport, bus
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to John Glenn Columbus International Airport (CMH)plane MSP - CMH
- Take the bus from Wilson & Ferrell Shell Station - Columbus to Toledo Bus Stopbus
9h 2m$480–1,090
Mayo Clinic to Toledo by foot and bus
Questions & Answers
The cheapest way to get from Mayo Clinic to Toledo is to drive which costs $100 - $160 and takes 9h 46m.
The fastest way to get from Mayo Clinic to Toledo is to bus and fly which takes 6h 55m and costs $150 - $550.
No, there is no direct bus from Mayo Clinic to Toledo. However, there are services departing from Rochester, MN and arriving at Toledo via 250 N. Lake St - Madison UW Campus and Chicago Union Station. The journey, including transfers, takes approximately 14h 17m.
The distance between Mayo Clinic and Toledo is 630 miles. The road distance is 589 miles.
The best way to get from Mayo Clinic to Toledo without a car is to bus which takes 14h 17m and costs $160 - $260.
It takes approximately 14h 17m to get from Mayo Clinic to Toledo, including transfers.
Mayo Clinic to Toledo bus services, operated by Jefferson Lines, depart from Rochester, MN station.
Mayo Clinic to Toledo bus services, operated by Jefferson Lines, arrive at UW-Madison station.
Yes, the driving distance between Mayo Clinic to Toledo is 589 miles. It takes approximately 9h 46m to drive from Mayo Clinic to Toledo.
There are 112+ hotels available in Toledo.
What companies run services between Mayo Clinic, MN, USA and Toledo, OH, USA?
You can take a vehicle from Mayo Clinic to Toledo via Rochester, MN, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 14h 17m.
- Website
- delta.com
Flights from Rochester to Detroit via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $160–900
Flights from Rochester to Detroit via Minneapolis–Saint Paul International Airport, Grand Rapids
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $160–900
Flights from Rochester to Detroit via Minneapolis–Saint Paul International Airport, Madison
- Ave. Duration
- 7h 34m
- When
- Thursday
- Estimated price
- $170–900
Flights from Minneapolis–Saint Paul International Airport to Detroit
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $95–550
Flights from Minneapolis–Saint Paul International Airport to Detroit via Iron Mountain
- Ave. Duration
- 3h 13m
- When
- Every day
- Estimated price
- $100–550
Flights from Minneapolis–Saint Paul International Airport to Detroit via Madison
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $95–550
Flights from Minneapolis–Saint Paul International Airport to Detroit via Milwaukee
- Ave. Duration
- 3h 52m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Minneapolis–Saint Paul International Airport to Detroit via Grand Rapids
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $95–550
Flights from Minneapolis–Saint Paul International Airport to Detroit via Traverse City
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $100–550
Flights from Minneapolis–Saint Paul International Airport to Fort Wayne International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $70–400
Flights from Minneapolis–Saint Paul International Airport to Fort Wayne International Airport via Detroit
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $85–440
Flights from Minneapolis–Saint Paul International Airport to Cleveland-Hopkins International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $110–600
Flights from Minneapolis–Saint Paul International Airport to Cleveland-Hopkins International Airport via Detroit
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $110–600
Flights from Minneapolis–Saint Paul International Airport to John Glenn Columbus International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $120–650
Flights from Minneapolis–Saint Paul International Airport to John Glenn Columbus International Airport via Detroit
- Ave. Duration
- 4h 13m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
- Website
- southwest.com
Flights from Minneapolis–Saint Paul International Airport to Cleveland-Hopkins International Airport via Chicago Midway
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $120–650
Flights from Minneapolis–Saint Paul International Airport to Cleveland-Hopkins International Airport via St. Louis
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $150–750
Flights from Minneapolis–Saint Paul International Airport to John Glenn Columbus International Airport via Chicago Midway
- Ave. Duration
- 3h 40m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $120–650
Flights from Minneapolis–Saint Paul International Airport to John Glenn Columbus International Airport via St. Louis
- Ave. Duration
- 3h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–750
Flights from Minneapolis–Saint Paul International Airport to John Glenn Columbus International Airport via Nashville
- Ave. Duration
- 4h 10m
- When
- Sunday
- Estimated price
- $170–800
- Website
- united.com
Flights from Rochester to Detroit via Chicago O'Hare
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $150–850
Flights from Minneapolis–Saint Paul International Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $70–400
Flights from Minneapolis–Saint Paul International Airport to Cleveland-Hopkins International Airport via Chicago O'Hare
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $120–650
Flights from Minneapolis–Saint Paul International Airport to John Glenn Columbus International Airport via Chicago O'Hare
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $120–650
- Website
- aa.com
Flights from Rochester to Detroit via Chicago O'Hare
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $150–850
Flights from Minneapolis–Saint Paul International Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $70–400
Flights from Minneapolis–Saint Paul International Airport to John Glenn Columbus International Airport via Chicago O'Hare
- Ave. Duration
- 4h 13m
- When
- Saturday
- Estimated price
- $120–650
- Website
- suncountry.com
Flights from Minneapolis–Saint Paul International Airport to Detroit
- Ave. Duration
- 1h 42m
- When
- Monday and Friday
- Estimated price
- $95–550
Flights from Minneapolis–Saint Paul International Airport to John Glenn Columbus International Airport
- Ave. Duration
- 1h 48m
- When
- Monday and Friday
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 32m
- Frequency
- 3 times a day
- Estimated price
- $130–270
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Toledo
- Ave. Duration
- 3h 59m
- Frequency
- 3 times a day
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Toledo
- Ave. Duration
- 3h 59m
- Frequency
- 3 times a day
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
Train from Cleveland Amtrak to Toledo
- Ave. Duration
- 2h 9m
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester, MN to UW-Madison
- Ave. Duration
- 4h 45m
- Frequency
- 3 times a day
- Estimated price
- $55–80
- Book at
- https://www.jeffersonlines.com
- Adult
- $55–80
Bus from Rochester to St. Paul
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Bus from Rochester, MN to UW-Madison
- Ave. Duration
- 4h 45m
- Frequency
- 3 times a day
- Estimated price
- $55–80
- Book at
- https://www.jeffersonlines.com
- Adult
- $55–80
Bus from Rochester, MN to Wisconsin Dells
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $45–65
- Book at
- https://www.jeffersonlines.com
- Adult
- $45–65
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- coachusa.com
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- coachusa.com
- Adult
- $26–60
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- coachusa.com
- Adult
- $26–60
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Chicago Union Station to Toledo
- Ave. Duration
- 3h 58m
- Frequency
- Twice a week
- Estimated price
- $85–120
- Website
- https://www.amtrak.com/home.html
Bus from Dearborn to Toledo
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $24–35
- Website
- https://www.amtrak.com/home.html
Bus from Dearborn to Toledo
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $24–35
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Wisconsin Dells to Chicago Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Toledo Bus Stop
- Ave. Duration
- 4h 50m
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Fort Wayne, IN to Toledo
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- $15–30
- Website
- https://www.greyhound.com/
Bus from Wilson & Ferrell Shell Station - Columbus to Toledo Bus Stop
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Website
- flixbus.com
Bus from Wisconsin Dells to Chicago Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- Twice daily
- Schedules at
- flixbus.com
- Website
- greyhound.com
Bus from Wisconsin Dells to Chicago Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Chicago Bus Station to Toledo Bus Stop
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Wilson & Ferrell Shell Station - Columbus to Toledo Bus Stop
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Schedules at
- greyhound.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Wisconsin Dells to Chicago Bus Station
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Toledo Bus Stop
- Ave. Duration
- 4h 40m
- Frequency
- 6 times a week
- Estimated price
- $35–65
- Schedules at
- flixbus.com
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Chicago Bus Station to Toledo Bus Stop
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $23–65
- Website
- https://baronsbus.com
Bus from Fort Wayne, IN to Toledo
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
- Website
- example.com
Bus from Chicago Bus Station to Toledo Bus Stop
- Ave. Duration
- 5h
- Frequency
- Once daily
- Schedules at
- example.com
Bus from Fort Wayne, IN to Toledo
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Schedules at
- example.com
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
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