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How to get fromMayo Clinic to Topekaby plane, car, shuttle, bus, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Mayo Clinic to Topeka by plane, car, shuttle, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Manhattan Regional Airport, drive

    best
    1. Fly from Rochester (RST) to Manhattan Regional Airport (MHK)plane plane RST - MHK
    2. Drive from Manhattan Regional Airport (MHK) to Topekacar car
    7h 15m
    $152–804

  2. Drive 462.9 mi

    cheapest
    1. Drive from Mayo Clinic to Topekacar car 462.9 mi
    7h 33m
    $85–122

  3. Shuttle, bus

    1. Take a shuttle bus from Rochester to Owatonna, MNshuttle bus
    2. Take the bus from Owatonna to Des Moinesbus bus
    3. Take the bus from Des Moines to Kansas Citybus bus
    4. Take the bus from Kansas City Bus Station to Topekabus bus
    12h 12m
    $115–201

  4. Fly Rochester to Kansas City, bus

    1. Fly from Rochester (RST) to Kansas City (MCI)plane plane RST - MCI
    2. Take the bus from 2745 Southwest Blvd - Kansas City to Quincy Street Station - Topekabus bus
    9h 19m
    $221–1,192

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Kansas City, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Kansas City (MCI)plane plane MSP - MCI
    3. Take the bus from 2745 Southwest Blvd - Kansas City to Quincy Street Station - Topekabus bus
    8h 4m
    $690–1,055

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Wichita Mid-Continent Airport, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Wichita Mid-Continent Airport (ICT)plane plane MSP - ICT
    3. Take the bus from 2210 Somerset St - Wichita to Quincy Street Station - Topekabus bus
    7h 44m
    $265–945

  7. Bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Take the bus from MSP Airport to Des Moinesbus bus
    3. Take the bus from Des Moines to Kansas Citybus bus
    4. Take the bus from Kansas City Bus Station to Topekabus bus
    14h 40m
    $174–234

Rochester (RST) to Manhattan Regional Airport (MHK) flights

Calendar21Weekly Planes
Duration5h 31mAverage Duration
Ticket$148Cheapest Price
See schedules

Questions & Answers

Map of how to get from Mayo Clinic to Topeka.ExpandLaunch map view
  • Distance: 466.4 mi
  • Duration: 7h 15m

What companies run services between Mayo Clinic, MN, USA and Topeka, KS, USA?

You can take a vehicle from Mayo Clinic to Topeka via Groome Transportation Office - Rochester, Minneapolis / St Paul Airport, MSP Airport, Des Moines, and Kansas City Bus Station in around 14h 40m.

Airlines
Bus operators

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