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How to get fromMayo Clinic to Torontoby plane, bus (Flixbus), bus, train, car, or shuttle

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There are 9 ways to get from Mayo Clinic to Toronto by plane, bus (Flixbus), bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Toronto Island Airport

    best
    1. Fly from Rochester (RST) to Toronto Island Airport (YTZ)plane plane RST - YTZ
    6h 34m
    $97–551

  2. Bus

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Torontobus bus
    21h 43m
    $212–333

  3. Bus, train via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo to Toronto Union Stationtrain train
    25h 38m
    $350–863

  4. Drive 1,377.8 km

    1. Drive from Mayo Clinic to Torontocar car 1,377.8 km
    14h 28m
    $271–392

  5. Fly Rochester to Toronto Pearson International Airport

    1. Fly from Rochester (RST) to Toronto Pearson International Airport (YYZ)plane plane RST - YYZ
    7h 31m
    $101–554

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Toronto Pearson International Airport

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Toronto Pearson International Airport (YYZ)plane plane MSP - YYZ
    6h 2m
    $498–1,582

  7. Fly Rochester to Buffalo Niagara International Airport, shuttle

    1. Fly from Rochester (RST) to Buffalo Niagara International Airport (BUF)plane plane RST - BUF
    2. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    8h 56m
    $281–1,024

  8. Bus to Minneapolis–Saint Paul International Airport, fly to Buffalo Niagara International Airport, shuttle

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Buffalo Niagara International Airport (BUF)plane plane MSP - BUF
    3. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    7h 31m
    $378–1,192

  9. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo to Toronto Union Stationtrain train
    26h 47m
    $430–1,085

Mayo Clinic to Toronto by foot and bus

Calendar4Weekly Services
Duration21h 43mAverage Duration
Ticket$212Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Toronto.ExpandLaunch map view
  • Distance: 1,064.7 km
  • Duration: 6h 34m

What companies run services between Mayo Clinic, MN, USA and Toronto, ON, Canada?

United Airlines, Air Canada, and two other airlines fly from Rochester (RST) to Toronto Island Airport (YTZ) 3 times a day. Alternatively, you can take a vehicle from Mayo Clinic to Toronto via Rochester, Milwaukee, Milwaukee Intermodal Station, and Detroit Bus Station in around 21h 43m.

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