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How to get fromMayo Clinic to Valparaisoby plane, bus, bus (Greyhound, Flixbus), train, or car

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There are 9 ways to get from Mayo Clinic to Valparaiso by plane, bus, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Chicago O'Hare International Airport, bus

    best
    1. Fly from Rochester (RST) to Chicago O'Hare International Airport (ORD)plane plane RST - ORD
    2. Take the bus from 350 S. Clark Street to 260 Brownbus bus
    5h 58m
    $39–300

  2. Bus

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Valparaisobus bus
    10h 48m
    $90–135

  3. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Van Buren St. to Gary Metro Centertrain train Ssl
    13h 16m
    $162–327

  4. Drive 395 mi

    1. Drive from Mayo Clinic to Valparaisocar car 395 mi
    6h 48m
    $73–105

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Chicago Midway International Airport, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago Midway International Airport (MDW)plane plane MSP - MDW
    3. Take the bus from 350 S. Clark Street to 260 Brownbus bus
    6h 50m
    $108–423

  6. Bus to Minneapolis–Saint Paul International Airport, fly to Chicago O'Hare International Airport, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago O'Hare International Airport (ORD)plane plane MSP - ORD
    3. Take the bus from 350 S. Clark Street to 260 Brownbus bus
    7h 2m
    $273–513

  7. Bus to Minneapolis–Saint Paul International Airport, fly to South Bend, train

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to South Bend (SBN)plane plane MSP - SBN
    3. Take the train from South Bend Airport to Garytrain train
    7h 42m
    $153–668

  8. Bus, train via Milwaukee

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Valparaisobus bus
    10h 51m
    $103–165

  9. Bus via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departuresbus bus
    3. Take the bus from 350 S. Clark Street to 260 Brownbus bus
    11h 19m
    $80–137

Mayo Clinic to Valparaiso by foot and bus

Calendar7Weekly Services
Duration10h 48mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Valparaiso.ExpandLaunch map view
  • Distance: 343.4 mi
  • Duration: 5h 58m

What companies run services between Mayo Clinic, MN, USA and Valparaiso, IN, USA?

You can take a vehicle from Mayo Clinic to Valparaiso via Rochester, Milwaukee, Milwaukee Intermodal Station, and Chicago Bus Station in around 10h 48m.

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Train operators
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