There are 3 ways to get from Mayo Clinic to Waterloo by shuttle, bus, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle, bus
best- Take a shuttle bus from Rochester to Owatonna, MN
- Take the bus from Owatonna to Des Moinesbus
- Take the bus from Des Moines to Waterloobus
9h 32m$74–147Drive 113.2 mi
cheapest- Drive from Mayo Clinic to Waterloocar 113.2 mi
2h 17m$21–30Bus
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Take the bus from MSP Airport to Des Moinesbus
- Take the bus from Des Moines to Waterloobus
12h$133–180
Questions & Answers
The cheapest way to get from Mayo Clinic to Waterloo is to drive which costs $20 - $30 and takes 2h 17m.
The fastest way to get from Mayo Clinic to Waterloo is to drive which takes 2h 17m and costs $20 - $30.
No, there is no direct bus from Mayo Clinic to Waterloo. However, there are services departing from Groome Transportation Office - Rochester and arriving at Waterloo via MSP Airport and Des Moines. The journey, including transfers, takes approximately 12h.
The distance between Mayo Clinic and Waterloo is 352 miles. The road distance is 113.8 miles.
The best way to get from Mayo Clinic to Waterloo without a car is to shuttle and bus which takes 9h 32m and costs $70 - $150.
It takes approximately 9h 32m to get from Mayo Clinic to Waterloo, including transfers.
Mayo Clinic to Waterloo bus services, operated by Groome Transportation, depart from Groome Transportation Office - Rochester station.
Mayo Clinic to Waterloo bus services, operated by Groome Transportation, arrive at Minneapolis / St Paul Airport station.
Yes, the driving distance between Mayo Clinic to Waterloo is 114 miles. It takes approximately 2h 17m to drive from Mayo Clinic to Waterloo.
There are 43+ hotels available in Waterloo.
What companies run services between Mayo Clinic, MN, USA and Waterloo, IA, USA?
You can take a vehicle from Mayo Clinic to Waterloo via Groome Transportation Office - Rochester, Minneapolis / St Paul Airport, MSP Airport, and Des Moines in around 12h.
- Phone
- +1 (888) 736-9190
- [email protected]
- Website
- landtoairexpress.com
Shuttle from Rochester to Owatonna, MN
- Ave. Duration
- 57 min
- Frequency
- Twice daily
- Estimated price
- $5–40
- Schedules at
- landtoairexpress.com
- Adult
- $5–40
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Owatonna to Des Moines
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $50–70
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–70
Bus from MSP Airport to Des Moines
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $65–90
- Book at
- https://www.jeffersonlines.com
- Adult
- $65–90
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Des Moines to Waterloo
- Ave. Duration
- 2h 55m
- Frequency
- 5 times a week
- Estimated price
- $18–40
- Website
- https://www.greyhound.com/
Bus from Des Moines to Waterloo
- Ave. Duration
- 2h 55m
- Frequency
- 5 times a week
- Estimated price
- $18–40
- Website
- https://www.greyhound.com/
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
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