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How to get fromMayo Clinic to West Des Moinesby shuttle, bus, taxi, car, plane, or bus (Greyhound)

Find Transport to West Des Moines

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There are 5 ways to get from Mayo Clinic to West Des Moines by shuttle, bus, taxi, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle, bus, taxi

    best
    1. Take a shuttle bus from Rochester to Owatonna, MNshuttle bus
    2. Take the bus from Owatonna to Amesbus bus
    3. Take the taxi from Ames to West Des Moinestaxi taxi
    5h 42m
    $126–202

  2. Drive 213.7 mi

    cheapest
    1. Drive from Mayo Clinic to West Des Moinescar car 213.7 mi
    3h 36m
    $39–57

  3. Fly from Rochester

    1. Fly from Rochester (RST) to Des Moines (DSM)plane plane RST - DSM
    5h 49m
    $98–608

  4. Bus

    1. Take the bus from Rochester to St. Paulbus bus Jefferson Lines 966
    2. Take the bus from Saint Paul Union Depot to Des Moinesbus bus Greyhound US0156
    8h 23m
    $87–137

  5. Bus to Minneapolis–Saint Paul International Airport, fly

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Des Moines (DSM)plane plane MSP - DSM
    3h 46m
    $152–671

Rochester (RST) to Des Moines (DSM) flights

Calendar62Weekly Planes
Duration6h 34mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to West Des Moines.ExpandLaunch map view
  • Distance: 229.7 mi
  • Duration: 5h 42m

What companies run services between Mayo Clinic, MN, USA and West Des Moines, IA, USA?

Delta, American Airlines, and United Airlines fly from Rochester (RST) to Des Moines (DSM) every 3 hours. Alternatively, you can take a vehicle from Mayo Clinic to West Des Moines via Rochester, Saint Paul Union Depot, and Des Moines in around 8h 23m.

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