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How to get fromMaysville to Chicagoby car, plane, taxi, bus, or train (Amtrak)

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There are 7 ways to get from Maysville to Chicago by car, plane, taxi, bus, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Blue Grass Airport, fly to Chicago O'Hare International Airport

    best
    1. Drive from Maysville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Chicago O'Hare International Airport (ORD)plane plane LEX - ORD
    4h 4m
    $70–393

  2. Drive 348.4 mi

    cheapest
    1. Drive from Maysville to Chicagocar car 348.4 mi
    6h 21m
    $64–92

  3. Taxi, bus

    1. Take the taxi from Maysville to Seamantaxi taxi
    2. Take the bus from Seaman to University of Cincinnatibus bus
    3. Take the bus from Cincinnati to Chicago Bus Stationbus bus
    9h 4m
    $118–201

  4. Train (Amtrak)

    1. Take the train from Maysville Station to Chicago Union Stationtrain train Cardinal
    10h 55m
    $128–270

  5. Drive to Louisville International Airport, fly to Chicago Midway International Airport

    1. Drive from Maysville to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW)plane plane SDF - MDW
    4h 31m
    $76–380

  6. Taxi, bus to Covington, fly to Chicago Midway International Airport

    1. Take the taxi from Maysville to Seamantaxi taxi
    2. Take the bus from Seaman to University of Cincinnatibus bus
    3. Fly from Covington (CVG) to Chicago Midway International Airport (MDW)plane plane CVG - MDW
    6h 12m
    $137–521

  7. Taxi, bus to Covington, fly to Chicago O'Hare International Airport

    1. Take the taxi from Maysville to Seamantaxi taxi
    2. Take the bus from Seaman to University of Cincinnatibus bus
    3. Fly from Covington (CVG) to Chicago O'Hare International Airport (ORD)plane plane CVG - ORD
    6h 40m
    $227–931

Blue Grass Airport (LEX) to Chicago O'Hare International Airport (ORD) flights

Calendar56Weekly Planes
Duration2h 7mAverage Duration
Ticket$59Cheapest Price
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Questions & Answers

Map of how to get from Maysville to Chicago.ExpandLaunch map view
  • Distance: 411.1 mi
  • Duration: 4h 4m

What companies run services between Maysville, KY, USA and Chicago, IL, USA?

Amtrak operates a train from Maysville Station to Chicago Union Station 3 times a week. Tickets cost $120–260 and the journey takes 10h 53m.

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