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How to get fromMaysville to Chicagoby car, plane, taxi, bus, or train (Amtrak)

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There are 8 ways to get from Maysville to Chicago by car, plane, taxi, bus, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Blue Grass Airport, fly to Chicago O'Hare International Airport

    best
    1. Drive from Maysville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Chicago O'Hare International Airport (ORD)plane plane LEX - ORD
    4h 1m
    $50–273

  2. Taxi, bus

    1. Take the taxi from Maysville to Seaman / Winchestertaxi taxi
    2. Take the bus from Seaman / Winchester to Cincinnatibus bus
    3. Take the bus from Cincinnati to Chicago Bus Stationbus bus
    8h 50m
    $118–190

  3. Train (Amtrak)

    1. Take the train from Maysville Station to Chicago Union Stationtrain train Cardinal
    10h 55m
    $218–340

  4. Drive  348.4 mi

    1. Drive from Maysville to Chicagocar car 348.4 mi
    6h 21m
    $64–92

  5. Drive to Dayton, fly to Chicago O'Hare International Airport

    1. Drive from Maysville to Dayton-Airport-DAYcar car
    2. Fly from Dayton (DAY) to Chicago O'Hare International Airport (ORD)plane plane DAY - ORD
    4h 43m
    $57–274

  6. Drive to Louisville International Airport, fly to Chicago Midway International Airport

    1. Drive from Maysville to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW)plane plane SDF - MDW
    4h 36m
    $81–440

  7. Taxi, bus to Covington, fly to Chicago Midway International Airport

    1. Take the taxi from Maysville to Seaman / Winchestertaxi taxi
    2. Take the bus from Seaman / Winchester to Cincinnatibus bus
    3. Fly from Covington (CVG) to Chicago Midway International Airport (MDW)plane plane CVG - MDW
    6h 3m
    $237–430

  8. Taxi, bus to Covington, fly to Chicago O'Hare International Airport

    1. Take the taxi from Maysville to Seaman / Winchestertaxi taxi
    2. Take the bus from Seaman / Winchester to Cincinnatibus bus
    3. Fly from Covington (CVG) to Chicago O'Hare International Airport (ORD)plane plane CVG - ORD
    6h 35m
    $227–880

Blue Grass Airport (LEX) to Chicago O'Hare International Airport (ORD) flights

Calendar81Weekly Planes
Duration2hAverage Duration
Ticket$38Cheapest Price
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Comparing Your Travel Options

Map of how to get from Maysville to Chicago.ExpandLaunch map view
  • Distance: 411.1 mi
  • Duration: 4h 1m

What companies run services between Maysville, KY, USA and Chicago, IL, USA?

Amtrak operates a train from Maysville Station to Chicago Union Station 3 times a week. Tickets cost $210–330 and the journey takes 10h 53m.

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