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How to get fromMaysville to Durhamby car, plane, taxi, bus, train (Amtrak), or train

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There are 8 ways to get from Maysville to Durham by car, plane, taxi, bus, train (Amtrak), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Blue Grass Airport, fly

    best
    1. Drive from Maysville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Raleigh-Durham International Airport (RDU)plane plane LEX - RDU
    6h 29m
    $89–484

  2. Drive  424.2 mi

    cheapest
    1. Drive from Maysville to Durhamcar car 424.2 mi
    7h 37m
    $78–112

  3. Taxi, bus

    1. Take the taxi from Maysville to Portsmouthtaxi taxi
    2. Take the bus from Portsmouth to Charlottebus bus
    3. Take the bus from Charlotte Bus Station to Durhambus bus
    12h 36m
    $182–272

  4. Train (Amtrak)

    1. Take the train from Maysville Station to Charlottesvilletrain train
    2. Take the train from Charlottesville to Greensborotrain train
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    17h 9m
    $358–570

  5. Drive to Tri-State Airport, fly

    1. Drive from Maysville to Tri-State Airport (HTS)car car
    2. Fly from Tri-State Airport (HTS) to Raleigh-Durham International Airport (RDU)plane plane HTS - RDU
    6h 33m
    $91–478

  6. Drive to Dayton, fly

    1. Drive from Maysville to Dayton-Airport-DAYcar car
    2. Fly from Dayton (DAY) to Raleigh-Durham International Airport (RDU)plane plane DAY - RDU
    5h 34m
    $106–515

  7. Taxi, bus to Covington, fly

    1. Take the taxi from Maysville to Seaman / Winchestertaxi taxi
    2. Take the bus from Seaman / Winchester to Cincinnatibus bus
    3. Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane plane CVG - RDU
    7h 8m
    $201–881

  8. Train, bus

    1. Take the train from Maysville Station to Charlottesvilletrain train
    2. Take the bus from Charlottesville Union Station to Fredericksburg Bus Stopbus bus
    3. Take the bus from Fredericksburg Bus Stop to Durhambus bus
    19h 40m
    $289–453

Blue Grass Airport (LEX) to Raleigh-Durham International Airport (RDU) flights

Calendar118Weekly Planes
Duration4h 25mAverage Duration
Ticket$74Cheapest Price
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Comparing Your Travel Options

Map of how to get from Maysville to Durham.ExpandLaunch map view
  • Distance: 440.2 mi
  • Duration: 6h 29m

What companies run services between Maysville, KY, USA and Durham, NC, USA?

You can take a vehicle from Maysville to Durham Amtrak Station via Maysville Station, Charlottesville, and Greensboro in around 17h 9m.

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