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How to get fromMaysville to Durhamby car, plane, train, bus, train (Amtrak), or taxi

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There are 6 ways to get from Maysville to Durham by car, plane, train, bus, train (Amtrak), or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Blue Grass Airport, fly

    best
    1. Drive from Maysville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Raleigh-Durham International Airport (RDU)plane plane LEX - RDU
    6h 36m
    $109–574

  2. Drive 424.2 mi

    cheapest
    1. Drive from Maysville to Durhamcar car 424.2 mi
    7h 37m
    $78–112

  3. Train, bus

    1. Take the train from Maysville Station to Ashland Amtrak Stationtrain train
    2. Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    12h 40m
    $93–180

  4. Train (Amtrak)

    1. Take the train from Maysville Station to Charlottesvilletrain train
    2. Take the train from Charlottesville to Greensborotrain train
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    17h 9m
    $210–450

  5. Train to Tri-State Airport, fly

    1. Take the train from Maysville Station to Ashland Amtrak Stationtrain train
    2. Fly from Tri-State Airport (HTS) to Raleigh-Durham International Airport (RDU)plane plane HTS - RDU
    8h 4m
    $120–460

  6. Taxi, bus to Covington, fly

    1. Take the taxi from Maysville to Seamantaxi taxi
    2. Take the bus from Seaman to University of Cincinnatibus bus
    3. Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane plane CVG - RDU
    7h 24m
    $291–572

Blue Grass Airport (LEX) to Raleigh-Durham International Airport (RDU) flights

Calendar146Weekly Planes
Duration5h 10mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Maysville to Durham.ExpandLaunch map view
  • Distance: 440.2 mi
  • Duration: 6h 36m

What companies run services between Maysville, KY, USA and Durham, NC, USA?

You can take a vehicle from Maysville to Durham Amtrak Station via Maysville Station, Charlottesville, and Greensboro in around 17h 9m.

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Other operators

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