There are 5 ways to get from Maysville to Roanoke by car, plane, train (Amtrak), taxi, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Blue Grass Airport, fly
best- Drive from Maysville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Roanoke Regional Airport-Woodrum Field (ROA)plane LEX - ROA
6h 21m$71–373Drive 306.2 mi
cheapest- Drive from Maysville to Roanokecar 306.2 mi
5h 46m$55–79Train (Amtrak)
- Take the train from Maysville Station to Charlottesvilletrain Cardinal
- Take the train from Charlottesville to Roanoketrain Northeast Regional
14h 8m$298–465Drive to Tri-State Airport, fly
- Drive from Maysville to Tri-State Airport (HTS)car
- Fly from Tri-State Airport (HTS) to Roanoke Regional Airport-Woodrum Field (ROA)plane HTS - ROA
6h 26m$73–366Taxi, bus to Covington, fly
- Take the taxi from Maysville to Seaman / Winchestertaxi
- Take the bus from Seaman / Winchester to Cincinnatibus
- Fly from Covington (CVG) to Roanoke Regional Airport-Woodrum Field (ROA)plane CVG - ROA
9h 2m$179–780
Blue Grass Airport (LEX) to Roanoke Regional Airport-Woodrum Field (ROA) flights
Comparing Your Travel Options
The cheapest way to get from Maysville to Roanoke is to drive which costs $50 - $80 and takes 5h 46m.
The fastest way to get from Maysville to Roanoke is to drive which takes 5h 46m and costs $50 - $80.
No, there is no direct train from Maysville station to Roanoke. However, there are services departing from Maysville Station and arriving at Roanoke via Charlottesville. The journey, including transfers, takes approximately 14h 8m.
The distance between Maysville and Roanoke is 337 miles. The road distance is 308 miles.
The best way to get from Maysville to Roanoke without a car is to train which takes 14h 8m and costs $290 - $470.
It takes approximately 6h 21m to get from Maysville to Roanoke, including transfers.
Maysville to Roanoke train services, operated by Amtrak, depart from Maysville Station.
Maysville to Roanoke train services, operated by Amtrak, arrive at Charlottesville station.
Yes, the driving distance between Maysville to Roanoke is 308 miles. It takes approximately 5h 46m to drive from Maysville to Roanoke.
Book your Maysville to Roanoke train tickets online with Omio.
What companies run services between Maysville, KY, USA and Roanoke, VA, USA?
You can take a vehicle from Maysville to Roanoke via Maysville Station and Charlottesville in around 14h 8m.
- Website
- aa.com
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $55–350
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Philadelphia
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $80–420
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $80–420
Flights from Tri-State Airport to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $55–340
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $100–650
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Philadelphia
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $130–750
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $130–700
- Website
- united.com
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $80–420
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Washington Dulles
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $110–650
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $130–700
- Website
- delta.com
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $70–390
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $130–700
Flights from Covington to Roanoke Regional Airport-Woodrum Field via New York La Guardia
- Ave. Duration
- 5h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–800
- Website
- allegiantair.com
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Orlando Sanford
- Ave. Duration
- 6h 49m
- When
- Monday and Friday
- Estimated price
- $190–900
Flights from Covington to Roanoke Regional Airport-Woodrum Field via St. Petersburg
- Ave. Duration
- 7h 52m
- When
- Thursday
- Estimated price
- $200–900
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Maysville Station to Charlottesville
- Ave. Duration
- 10h 33m
- Frequency
- 3 times a week
- Estimated price
- $230–360
- Website
- Amtrak
Train from Charlottesville to Roanoke
- Ave. Duration
- 2h 33m
- Frequency
- Twice daily
- Estimated price
- $60–95
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Seaman / Winchester to Cincinnati
- Ave. Duration
- 1h 10m
- Frequency
- Twice daily
- Estimated price
- $5–40
- Website
- Barons Bus
- Phone
- +1 888 954 6287
- [email protected]
- Website
- Go bus
Bus from Seaman / Winchester to Cincinnati
- Ave. Duration
- 1h 24m
- Frequency
- Twice daily
- Estimated price
- $9–12
- Website
- Go bus
- Book at
- Go bus booking
- Ave. Duration
- 40 min
- Estimated price
- $65–85
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 95+ hotels available in Roanoke.









