There are 7 ways to get from Maysville to Roanoke by train, bus, car, plane, train (Amtrak), or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Maysville Station to Ashland Amtrak Stationtrain
- Take the bus from Ashland to Wythevillebus
- Take the bus from Rural King Shopping Center to Route 460 Park and Ridebus
- Take the bus from Exit 118 - Park and Ride to Roanoke Campbell Courtbus Swb
11h 21m$87–188Drive 306.2 mi
cheapest- Drive from Maysville to Roanokecar 306.2 mi
5h 50m$56–81Train, bus via Charlottesville
- Take the train from Maysville Station to Charlottesvilletrain Cardinal
- Take the bus from Charlottesville Union Station to Roanoke Bus Stopbus Greyhound US0600
14h$156–325Drive to Blue Grass Airport, fly
- Drive from Maysville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Roanoke Regional Airport-Woodrum Field (ROA)plane LEX - ROA
7h$97–503Train (Amtrak)
- Take the train from Maysville Station to Charlottesvilletrain Cardinal
- Take the train from Charlottesville to Roanoketrain Northeast Regional
14h 8m$173–365Train to Tri-State Airport, fly
- Take the train from Maysville Station to Ashland Amtrak Stationtrain
- Fly from Tri-State Airport (HTS) to Roanoke Regional Airport-Woodrum Field (ROA)plane HTS - ROA
7h 36m$113–419Taxi, bus to Covington, fly
- Take the taxi from Maysville to Marathon Gas Stationtaxi
- Take the bus from Marathon Gas Station to University of Cincinnatibus
- Fly from Covington (CVG) to Roanoke Regional Airport-Woodrum Field (ROA)plane CVG - ROA
8h 58m$164–610
Blue Grass Airport (LEX) to Roanoke Regional Airport-Woodrum Field (ROA) flights
Questions & Answers
The cheapest way to get from Maysville to Roanoke is to drive which costs $55 - $85 and takes 5h 50m.
The fastest way to get from Maysville to Roanoke is to drive which takes 5h 50m and costs $55 - $85.
No, there is no direct train from Maysville station to Roanoke. However, there are services departing from Maysville Station and arriving at Roanoke via Charlottesville. The journey, including transfers, takes approximately 14h 8m.
The distance between Maysville and Roanoke is 379 miles. The road distance is 308 miles.
The best way to get from Maysville to Roanoke without a car is to train and bus which takes 11h 21m and costs $85 - $190.
It takes approximately 11h 21m to get from Maysville to Roanoke, including transfers.
Maysville to Roanoke train services, operated by Amtrak, depart from Maysville Station.
Maysville to Roanoke train services, operated by Amtrak, arrive at Charlottesville station.
Yes, the driving distance between Maysville to Roanoke is 308 miles. It takes approximately 5h 50m to drive from Maysville to Roanoke.
Book your Maysville to Roanoke train tickets online with Omio.
What companies run services between Maysville, KY, USA and Roanoke, VA, USA?
You can take a vehicle from Maysville to Roanoke via Maysville Station and Charlottesville in around 14h 8m.
- Website
- aa.com
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $80–480
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $120–650
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Philadelphia
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $120–600
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Dallas/Ft.Worth
- Ave. Duration
- 9h 24m
- When
- Every day
- Estimated price
- $220–900
Flights from Tri-State Airport to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $50–320
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Charlotte
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $85–480
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $110–600
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Philadelphia
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $110–600
- Website
- delta.com
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $100–550
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $110–550
Flights from Covington to Roanoke Regional Airport-Woodrum Field via New York La Guardia
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from Blue Grass Airport to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 7h 9m
- When
- Every day
- Estimated price
- $120–650
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Washington Dulles
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $90–500
Flights from Covington to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Maysville Station to Ashland Amtrak Station
- Ave. Duration
- 1h 43m
- Frequency
- 3 times a week
- Estimated price
- $27–55
- Website
- https://www.amtrak.com/home.html
Train from Maysville Station to Charlottesville
- Ave. Duration
- 10h 33m
- Frequency
- 3 times a week
- Estimated price
- $130–280
- Website
- https://www.amtrak.com/home.html
Train from Maysville Station to Charlottesville
- Ave. Duration
- 10h 33m
- Frequency
- 3 times a week
- Estimated price
- $130–280
- Website
- https://www.amtrak.com/home.html
Train from Charlottesville to Roanoke
- Ave. Duration
- 2h 33m
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- https://www.amtrak.com/home.html
Train from Maysville Station to Ashland Amtrak Station
- Ave. Duration
- 1h 43m
- Frequency
- 3 times a week
- Estimated price
- $27–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Ashland to Wytheville
- Ave. Duration
- 4h 40m
- Frequency
- Once daily
- Estimated price
- $19–60
- Website
- https://baronsbus.com
Bus from Marathon Gas Station to University of Cincinnati
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $5–40
- Website
- https://baronsbus.com
- Phone
- +1-877-462-6342
- [email protected]
- Website
- us.megabus.com
Bus from Rural King Shopping Center to Route 460 Park and Ride
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $12–35
- Website
- https://us.megabus.com
- Adult One-way
- $12–35
- Phone
- +1-800-827-3490
- [email protected]
- Website
- virginiabreeze.drpt.virginia.gov
Bus from Rural King Shopping Center to Route 460 Park and Ride
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $17–22
- Schedules at
- virginiabreeze.drpt.virginia.gov
- Phone
- +1 540 982 2222
- [email protected]
- Website
- valleymetro.com
Bus from Exit 118 - Park and Ride to Roanoke Campbell Court
- Ave. Duration
- 48 min
- Frequency
- Every 3 hours
- Estimated price
- $1–4
- Website
- https://www.valleymetro.com
- Website
- greyhound.com
Bus from Charlottesville Union Station to Roanoke Bus Stop
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Charlottesville Union Station to Roanoke Bus Stop
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
- Website
- example.com
Bus from Marathon Gas Station to University of Cincinnati
- Ave. Duration
- 1h 15m
- Frequency
- Twice daily
- Schedules at
- example.com
- Website
- example.com
Bus from Marathon Gas Station to University of Cincinnati
- Ave. Duration
- 1h 10m
- Frequency
- Twice daily
- Schedules at
- example.com
- Ave. Duration
- 40 min
- Estimated price
- $65–85
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 89+ hotels available in Roanoke.













