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How to get fromMaysville to St. Louisby train, bus, taxi, car, or plane

Find Transport to St. Louis

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There are 6 ways to get from Maysville to St. Louis by train, bus, taxi, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Maysville Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    10h 20m
    $143–235

  2. Drive  391.4 mi

    cheapest
    1. Drive from Maysville to St. Louiscar car 391.4 mi
    6h 54m
    $72–104

  3. Taxi, bus

    1. Take the taxi from Maysville to Seaman / Winchestertaxi taxi
    2. Take the bus from Seaman / Winchester to Cincinnatibus bus
    3. Take the bus from Cincinnati to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    11h
    $122–235

  4. Drive to Louisville International Airport, fly

    1. Drive from Maysville to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane plane SDF - STL
    6h 42m
    $122–638

  5. Taxi, bus to Covington, fly

    1. Take the taxi from Maysville to Seaman / Winchestertaxi taxi
    2. Take the bus from Seaman / Winchester to Cincinnatibus bus
    3. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    8h 14m
    $678–1,078

  6. Taxi, bus, bus to John Glenn Columbus International Airport, fly

    1. Take the taxi from Maysville to Seaman / Winchestertaxi taxi
    2. Take the bus from Seaman / Winchester to Athensbus bus
    3. Take the bus from Athens, Ohio OU Baker Center to John Glenn Columbus Intnl Airport (CMH)bus bus
    4. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    8h 18m
    $908–1,118

Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL) flights

Calendar114Weekly Planes
Duration4h 34mAverage Duration
Ticket$99Cheapest Price
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Comparing Your Travel Options

Map of how to get from Maysville to St. Louis.ExpandLaunch map view
  • Distance: 430.8 mi
  • Duration: 10h 20m

What companies run services between Maysville, KY, USA and St. Louis, MO, USA?

There is no direct connection from Maysville to St. Louis. However, you can take the taxi to Maysville Station, take the train to Indianapolis, walk to Indianapolis Union Station, then take the bus to St Louis Bus Station. Alternatively, you can take the taxi to Seaman / Winchester, take the bus to Cincinnati, take the bus to Indianapolis, then take the bus to St Louis Bus Station.

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