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How to get fromMaysville to St. Louisby train, bus, taxi, car, or plane

Find Transport to St. Louis

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There are 5 ways to get from Maysville to St. Louis by train, bus, taxi, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Maysville Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    10h 20m
    $88–180

  2. Drive  391.4 mi

    cheapest
    1. Drive from Maysville to St. Louiscar car 391.4 mi
    6h 54m
    $72–104

  3. Taxi, bus

    1. Take the taxi from Maysville to Seamantaxi taxi
    2. Take the bus from Seaman to Greyhound Station Cincinnatibus bus
    3. Take the bus from Greyhound Station Cincinnati to Indianapolis, INbus bus
    4. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    11h
    $122–231

  4. Taxi, bus to Covington, fly

    1. Take the taxi from Maysville to Seaman / Winchestertaxi taxi
    2. Take the bus from Seaman / Winchester to Cincinnatibus bus
    3. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    8h 9m
    $678–1,078

  5. Train, bus to John Glenn Columbus International Airport, fly

    1. Take the train from Maysville Station to Ashland Amtrak Stationtrain train
    2. Take the bus from Ashland Bus Station to Wilson & Ferrell Shell Station - Columbusbus bus
    3. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    9h 38m
    $858–1,008

Covington (CVG) to Lambert–St. Louis International Airport (STL) flights

Calendar124Weekly Planes
Duration4h 10mAverage Duration
Ticket$116Cheapest Price
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Questions & Answers

Map of how to get from Maysville to St. Louis.ExpandLaunch map view
  • Distance: 430.8 mi
  • Duration: 10h 20m

What companies run services between Maysville, KY, USA and St. Louis, MO, USA?

There is no direct connection from Maysville to St. Louis. However, you can take the taxi to Maysville Station, take the train to Indianapolis, walk to Indianapolis Union Station, then take the bus to St Louis Bus Station. Alternatively, you can take the taxi to Seaman, take the bus to Greyhound Station Cincinnati, take the bus to Indianapolis, IN, then take the bus to St Louis Bus Station.

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