Rome2Rio

How to get fromMaysville to St. Louisby taxi, bus, train, car, or plane

Find Transport to St. Louis

See all options

There are 6 ways to get from Maysville to St. Louis by taxi, bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus

    best
    1. Take the taxi from Maysville to Marathon Gas Stationtaxi taxi
    2. Take the bus from Marathon Gas Station to Greyhound Bus Depotbus bus
    3. Take the bus from Cincinnati Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    10h 15m
    $169–260

  2. Drive 391.4 mi

    cheapest
    1. Drive from Maysville to St. Louiscar car 391.4 mi
    6h 54m
    $72–104

  3. Train, bus

    1. Take the train from Maysville Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    10h 20m
    $128–230

  4. Taxi, bus to Covington, fly

    1. Take the taxi from Maysville to Marathon Gas Stationtaxi taxi
    2. Take the bus from Marathon Gas Station to University of Cincinnatibus bus
    3. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    8h 14m
    $198–828

  5. Train, bus via Champaign

    1. Take the train from Maysville Station to Indianapolistrain train
    2. Take the bus from Indianapolis to Champaignbus bus
    3. Take the bus from Champaign Intermodal Trans Ctr to St Louis Bus Stationbus bus
    12h 50m
    $132–245

  6. Train, bus to John Glenn Columbus International Airport, fly

    1. Take the train from Maysville Station to Ashland Amtrak Stationtrain train
    2. Take the bus from Ashland Bus Station to Columbusbus bus
    3. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    9h 18m
    $850–1,058

Covington (CVG) to Lambert–St. Louis International Airport (STL) flights

Calendar125Weekly Planes
Duration4h 7mAverage Duration
Ticket$126Cheapest Price
See schedules

Questions & Answers

Map of how to get from Maysville to St. Louis.ExpandLaunch map view
  • Distance: 441.5 mi
  • Duration: 10h 15m

What companies run services between Maysville, KY, USA and St. Louis, MO, USA?

There is no direct connection from Maysville to St. Louis. However, you can take the taxi to Marathon Gas Station, take the bus to Greyhound Bus Depot, walk to Cincinnati Bus Station, take the bus to Indianapolis Union Station, then take the bus to St Louis Bus Station. Alternatively, you can take a vehicle from Maysville to St Louis Bus Station via Maysville Station, Indianapolis, and Indianapolis Union Station in around 10h 20m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound