There are 6 ways to get from McAllen to Florida Keys by plane, bus (Greyhound, Flixbus), car, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Mcallen Miller International Airport to Key West International Airport
best- Fly from Mcallen Miller International Airport (MFE) to Key West International Airport (EYW)plane MFE - EYW
9h 27m$183–551Bus
- Take the bus from McAllen Central Station to Houston Bus Stationbus
- Take the bus from Houston - Harrisburg Blvd to Miamibus
- Take the bus from Miami Airport Station to Big Pine Keybus
37h 58m$274–391Drive 1,655.7 mi
- Drive from McAllen to Florida Keyscar 1,655.7 mi
29h 21m$303–437Fly Mcallen Miller International Airport to Miami International Airport, shuttle
- Fly from Mcallen Miller International Airport (MFE) to Miami International Airport (MIA)plane MFE - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 51m$258–661Fly Mcallen Miller International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Mcallen Miller International Airport (MFE) to Fort Lauderdale–Hollywood International Airport (FLL)plane MFE - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
10h 56m$288–761Bus to Rio Grande Valley International Airport, fly to Key West International Airport
- Take the bus from McAllen Central Station to Harlingen Bus Stationbus
- Fly from Rio Grande Valley International Airport (HRL) to Key West International Airport (EYW)plane HRL - EYW
14h 29m$214–586
Mcallen Miller International Airport (MFE) to Key West International Airport (EYW) flights
Comparing Your Travel Options
The cheapest way to get from McAllen to Florida Keys is to bus which costs $270 - $400 and takes 37h 58m.
The fastest way to get from McAllen to Florida Keys is to fly which takes 9h 27m and costs $180 - $550.
No, there is no direct bus from McAllen station to Florida Keys. However, there are services departing from McAllen Central Station and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Houston - Harrisburg Blvd, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 37h 58m.
The distance between McAllen and Florida Keys is 1064 miles. The road distance is 1665.4 miles.
The best way to get from McAllen to Florida Keys without a car is to bus which takes 37h 58m and costs $270 - $400.
It takes approximately 9h 27m to get from McAllen to Florida Keys, including transfers.
McAllen to Florida Keys bus services, operated by Greyhound USA, depart from McAllen Central Station.
The best way to get from McAllen to Florida Keys is to fly which takes 9h 27m and costs $180 - $550. Alternatively, you can bus, which costs $270 - $400 and takes 37h 58m.
McAllen to Florida Keys bus services, operated by Greyhound USA, arrive at Houston Bus Station.
Yes, the driving distance between McAllen to Florida Keys is 1665 miles. It takes approximately 29h 21m to drive from McAllen to Florida Keys.
What companies run services between McAllen, TX, USA and Florida Keys, FL, USA?
American Airlines flies from Mcallen Miller International Airport (MFE) to Key West International Airport (EYW) once daily. Alternatively, you can take a bus from McAllen Central Station to Florida Keys via Houston Bus Station, Houston - Harrisburg Blvd, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 37h 58m.
- Website
- aa.com
Flights from Mcallen Miller International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $100–450
Flights from Mcallen Miller International Airport to Miami International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 53m
- When
- Saturday to Friday
- Estimated price
- $110–550
Flights from Mcallen Miller International Airport to Miami International Airport via Phoenix
- Ave. Duration
- 8h 22m
- When
- Every day
- Estimated price
- $190–800
Flights from Mcallen Miller International Airport to Fort Lauderdale–Hollywood International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $130–600
Flights from Rio Grande Valley International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 10h 14m
- When
- Every day
- Estimated price
- $100–450
Flights from Rio Grande Valley International Airport to Key West International Airport via Austin, Miami International Airport
- Ave. Duration
- 8h 34m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $95–440
- Website
- united.com
Flights from Mcallen Miller International Airport to Miami International Airport via Houston
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $100–470
Flights from Mcallen Miller International Airport to Fort Lauderdale–Hollywood International Airport via Houston
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $110–550
- Website
- delta.com
Flights from Mcallen Miller International Airport to Miami International Airport via Austin
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $100–490
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from McAllen Central Station to Houston Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- Twice daily
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from McAllen Central Station to Houston Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- $55–85
- Schedules at
- Flixbus USA
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Miami
- Ave. Duration
- 24h 14m
- Frequency
- Once daily
- Estimated price
- $180–240
- Schedules at
- Omnibus Express
Bus from McAllen Central Station to Harlingen Bus Station
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Omnibus Express
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are 964+ hotels available in Florida Keys.






