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How to get fromMcAllen to Knoxvilleby plane, bus, train, taxi, shuttle, car, bus (Greyhound, Flixbus), or bus (Greyhound)

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There are 8 ways to get from McAllen to Knoxville by plane, bus, train, taxi, shuttle, car, bus (Greyhound, Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Mcallen Miller International Airport (MFE) to Mcghee Tyson Airport (TYS)plane plane MFE - TYS
    5h 7m
    $311–1,277

  2. Drive 1,247.2 mi

    cheapest
    1. Drive from McAllen to Knoxvillecar car 1,247.2 mi
    22h 14m
    $228–329

  3. Bus, train, taxi, shuttle, drive

    1. Take the bus from McAllen Central Station to San Antoniobus bus
    2. Take the train from San Antonio Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train
    4. Take the bus from Forsyth Hospital to Boonebus bus
    5. Take the taxi from Boone to Black Bear Resorttaxi taxi
    6. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    7. Drive from Hot Springs to Knoxvillecar car
    2d 3h

  4. Bus

    1. Take the bus from McAllen Central Station to Houston - Telephone Rdbus bus
    2. Take the bus from Houston Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to New York Midtownbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    2d 7h
    $523–895

  5. Fly to Chattanooga Metropolitan Airport, drive

    1. Fly from Mcallen Miller International Airport (MFE) to Chattanooga Metropolitan Airport (CHA)plane plane MFE - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    6h 39m
    $264–1,235

  6. Bus via Sandy Springs

    1. Take the bus from McAllen Central Station to Houston - Harrisburg Blvdbus bus
    2. Take the bus from Houston - Harrisburg Blvd to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to Port Authority Bus Terminalbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    2d 8h
    $531–800

  7. Bus, train

    1. Take the bus from McAllen Central Station to Houston - Telephone Rdbus bus
    2. Take the bus from Houston Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d 13h
    $693–1,315

  8. Bus, train via Farragut

    1. Take the bus from McAllen Central Station to Houston Bus Stationbus bus
    2. Take the train from Houston to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    2d 16h
    $783–1,506

Mcallen Miller International Airport (MFE) to Mcghee Tyson Airport (TYS) flights

Calendar47Weekly Planes
Duration6h 5mAverage Duration
Ticket$251Cheapest Price
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Questions & Answers

Map of how to get from McAllen to Knoxville.ExpandLaunch map view
  • Distance: 1,087.4 mi
  • Duration: 5h 7m

What companies run services between McAllen, TX, USA and Knoxville, TN, USA?

American Airlines, United Airlines, and Allegiant Air fly from Mcallen Miller International Airport (MFE) to Mcghee Tyson Airport (TYS) every 4 hours. Alternatively, you can take a bus from McAllen Central Station to Knoxville via Houston - Telephone Rd, S Wayside Dr @ Telephone Rd, Magnolia Transit Center, Houston Bus Station, Atlanta Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 2d 7h.

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