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How to get fromMeadville to Louisvilleby bus (Greyhound, Amtrak), car, bus, plane, or bus (Greyhound, Flixbus, Amtrak)

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There are 6 ways to get from Meadville to Louisville by bus (Greyhound, Amtrak), car, bus, plane, or bus (Greyhound, Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Meadville to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 5m
    $98–164

  2. Drive  420.7 mi

    cheapest
    1. Drive from Meadville to Louisvillecar car 420.7 mi
    7h 28m
    $77–111

  3. Bus to Erie International Airport, fly

    1. Take the bus from Meadville to Eriebus bus
    2. Fly from Erie International Airport (ERI) to Louisville International Airport (SDF)plane plane ERI - SDF
    10h 25m
    $131–717

  4. Bus via Columbus

    1. Take the bus from Meadville to Eriebus bus
    2. Take the bus from Erie to Columbusbus bus
    3. Take the bus from Columbus to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 47m
    $94–163

  5. Bus, bus to Cleveland-Hopkins International Airport, fly

    1. Take the bus from Meadville to Eriebus bus
    2. Take the bus from Erie to Cleveland Bus Stationbus bus
    3. Fly from Cleveland-Hopkins International Airport (CLE) to Louisville International Airport (SDF)plane plane CLE - SDF
    9h 57m
    $138–795

  6. Bus to Pittsburgh International Airport, fly

    1. Take the bus from Meadville to Pittsburgh Intermodal Stationbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Louisville International Airport (SDF)plane plane PIT - SDF
    7h 30m
    $277–1,727

Meadville to Louisville by bus

Calendar7Weekly Buses
Duration14h 5mAverage Duration
Ticket$98Cheapest Price
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Comparing Your Travel Options

Map of how to get from Meadville to Louisville.ExpandLaunch map view
  • Distance: 578.1 mi
  • Duration: 14h 5m

What companies run services between Meadville, Crawford County, PA, USA and Louisville, KY, USA?

You can take a bus from Meadville to Louisville, KY via Pittsburgh Intermodal Station and Indianapolis Union Station in around 14h 5m.

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