There are 3 ways to get from Mechanicsburg to St. Louis by bus (Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Springfield SMTD Transfer Center to St Louis Bus Stationbus FlixBus N2521 / ...
2h 4m$56–74Drive 110.4 mi
cheapest- Drive from Mechanicsburg to St. Louiscar 110.4 mi
1h 59m$21–30Train (Amtrak)
- Take the train from Springfield to St. Louistrain Lincoln Service / ...
2h 13m$73–115
Questions & Answers
The cheapest way to get from Mechanicsburg to St. Louis is to drive which costs $20 - $30 and takes 1h 59m.
The fastest way to get from Mechanicsburg to St. Louis is to drive which takes 1h 59m and costs $20 - $30.
No, there is no direct bus from Mechanicsburg to St. Louis station. However, there are services departing from Springfield SMTD Transfer Center and arriving at St Louis Bus Station via . The journey, including transfers, takes approximately 2h 4m.
No, there is no direct train from Mechanicsburg to St. Louis. However, there are services departing from Springfield and arriving at St. Louis via . The journey, including transfers, takes approximately 2h 13m.
The distance between Mechanicsburg and St. Louis is 113 miles. The road distance is 111 miles.
The best way to get from Mechanicsburg to St. Louis without a car is to bus which takes 2h 4m and costs $55 - $75.
It takes approximately 2h 4m to get from Mechanicsburg to St. Louis, including transfers.
Mechanicsburg to St. Louis bus services, operated by Flixbus USA, depart from Springfield SMTD Transfer Center station.
Mechanicsburg to St. Louis train services, operated by Amtrak, depart from Springfield station.
The best way to get from Mechanicsburg to St. Louis is to bus which takes 2h 4m and costs $55 - $75. Alternatively, you can train, which costs $70 - $120 and takes 2h 13m.
What companies run services between Mechanicsburg, IL, USA and St. Louis, MO, USA?
Flixbus USA operates a bus from Springfield SMTD Transfer Center to St Louis Bus Station 4 times a day. Tickets cost $15–25 and the journey takes 1h 40m. Alternatively, Amtrak operates a train from Springfield to St. Louis 5 times a day. Tickets cost $30–65 and the journey takes 1h 48m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Springfield to St. Louis
- Ave. Duration
- 1h 48m
- Frequency
- 5 times a day
- Estimated price
- $30–65
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Springfield SMTD Transfer Center to St Louis Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $15–25
- Schedules at
- Flixbus USA
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More Questions & Answers
Mechanicsburg to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Mechanicsburg to St. Louis train services, operated by Amtrak, arrive at St. Louis station.
Yes, the driving distance between Mechanicsburg to St. Louis is 111 miles. It takes approximately 1h 59m to drive from Mechanicsburg to St. Louis.
There are 482+ hotels available in St. Louis.







