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How to get fromMechanicsburg to Buffaloby bus (Greyhound), car, train, plane, or bus

Find Transport to Buffalo

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There are 4 ways to get from Mechanicsburg to Buffalo by bus (Greyhound), car, train, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Harrisburg, Pa to Scranton, Pabus bus 770
    2. Take the bus from Scranton Bus Station to Buffalobus bus Greyhound US0205 / ...
    11h 27m
    $65–147

  2. Drive  288.7 mi

    cheapest
    1. Drive from Mechanicsburg to Buffalocar car 288.7 mi
    5h 45m
    $53–77

  3. Train, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    7h 40m
    $148–724

  4. Bus via Sandy

    1. Take the bus from Harrisburg, Pa to Dubois, Pabus bus 731
    2. Take the bus from DuBois to Buffalobus bus Fab510
    11h 57m
    $58–202

Mechanicsburg to Buffalo by bus and foot

Calendar7Weekly Services
Duration11h 27mAverage Duration
Ticket$65Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mechanicsburg to Buffalo.ExpandLaunch map view
  • Distance: 403 mi
  • Duration: 11h 27m

What companies run services between Mechanicsburg, Cumberland County, PA, USA and Buffalo, NY, USA?

You can take a bus from E Main St & Arch St EB to Buffalo via Market Square Transfer Center, Harrisburg, Pa, and Scranton Bus Station in around 11h 27m.

Airlines
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