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How to get fromMechanicsburg to Clevelandby bus, train (Amtrak), car, train, or plane

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There are 5 ways to get from Mechanicsburg to Cleveland by bus, train (Amtrak), car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Harrisburg Bus Station to Cleveland Bus Stationbus bus Greyhound US0420
    9h 2m
    $81–112

  2. Drive 316.3 mi

    cheapest
    1. Drive from Mechanicsburg to Clevelandcar car 316.3 mi
    5h 31m
    $58–84

  3. Train (Amtrak)

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train Pennsylvanian
    2. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train Floridian
    10h 54m
    $121–252

  4. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Cleveland-Hopkins International Airport (CLE)plane plane PHL - CLE
    7h 11m
    $207–508

  5. Train, train to Baltimore-Washington International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Cleveland-Hopkins International Airport (CLE)plane plane BWI - CLE
    8h 5m
    $178–1,375

Mechanicsburg to Cleveland by bus and foot

Calendar7Weekly Services
Duration9h 2mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Mechanicsburg to Cleveland.ExpandLaunch map view
  • Distance: 336 mi
  • Duration: 9h 2m

What companies run services between Mechanicsburg, Cumberland County, PA, USA and Cleveland, OH, USA?

Jefferson Lines operates a bus from Harrisburg Bus Station to Cleveland Bus Station once daily. Tickets cost $80–110 and the journey takes 7h 30m. Alternatively, you can take a bus from E Main St & Race St EB to Cleveland Amtrak via Market Square Transfer Center, Harrisburg, and Pittsburgh Amtrak Station in around 10h 54m.

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