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How to get fromMechanicsburg to Clevelandby bus (Flixbus), train (Amtrak), car, train, plane, or bus (Greyhound)

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There are 6 ways to get from Mechanicsburg to Cleveland by bus (Flixbus), train (Amtrak), car, train, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via State College Airport (SCE)

    best
    1. Take the bus from Harrisburg Bus Station to State College Regional Airportbus bus
    2. Take the bus from State College Regional Airport to Robert K Pfaff Transit Center - Akronbus bus
    3. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland, OHbus bus
    10h 22m
    $47–114

  2. Train (Amtrak)

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train Pennsylvanian
    2. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train Floridian
    10h 54m
    $96–232

  3. Drive  316.3 mi

    1. Drive from Mechanicsburg to Clevelandcar car 316.3 mi
    5h 31m
    $58–84

  4. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Cleveland-Hopkins International Airport (CLE)plane plane PHL - CLE
    7h 7m
    $203–498

  5. Bus (Greyhound)

    1. Take the bus from Harrisburg Bus Station to Cleveland Bus Stationbus bus Greyhound US0420
    10h 53m
    $54–105

  6. Train, train to Baltimore-Washington International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Cleveland-Hopkins International Airport (CLE)plane plane BWI - CLE
    8h 5m
    $174–1,265

Mechanicsburg to Cleveland by bus and foot

Calendar5Weekly Services
Duration10h 22mAverage Duration
Ticket$47Cheapest Price
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Questions & Answers

Map of how to get from Mechanicsburg to Cleveland.ExpandLaunch map view
  • Distance: 355.5 mi
  • Duration: 10h 22m

What companies run services between Mechanicsburg, Cumberland County, PA, USA and Cleveland, OH, USA?

You can take a bus from E Main St & Arch St EB to Cleveland, OH via Market Square Transfer Center, Harrisburg Bus Station, State College Regional Airport, and Robert K Pfaff Transit Center - Akron in around 10h 22m. Alternatively, you can take a bus from E Main St & Race St EB to Cleveland Amtrak via Market Square Transfer Center, Harrisburg, and Pittsburgh Amtrak Station in around 10h 54m.

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