There are 4 ways to get from Mechanicsburg to Erie by bus (Greyhound, Flixbus), train, bus, car, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Harrisburg Bus Station to Pittsburgh Intermodal Stationbus Greyhound US0420 / ...
- Take the bus from Pittsburgh Intermodal Station to Eriebus Greyhound US0440s
9h 52m$57–97Drive 264.3 mi
cheapest- Drive from Mechanicsburg to Eriecar 264.3 mi
5h 50m$47–68Train, bus
- Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain Pennsylvanian
- Take the bus from Pittsburgh Intermodal Station to Eriebus Greyhound US0440s
11h 20m$157–252Train (Amtrak)
- Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain
- Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain
- Take the train from Cleveland Amtrak to Erie Stationtrain
13h 22m$256–412
Mechanicsburg to Erie by bus and foot
Comparing Your Travel Options
The cheapest way to get from Mechanicsburg to Erie is to drive which costs $45 - $70 and takes 5h 50m.
The fastest way to get from Mechanicsburg to Erie is to drive which takes 5h 50m and costs $45 - $70.
No, there is no direct bus from Mechanicsburg to Erie. However, there are services departing from E Main St & Arch St EB and arriving at Erie via Harrisburg Bus Station and Pittsburgh Intermodal Station. The journey, including transfers, takes approximately 9h 52m.
No, there is no direct train from Mechanicsburg to Erie station. However, there are services departing from Harrisburg and arriving at Erie Station via Pittsburgh Amtrak Station and Cleveland Amtrak. The journey, including transfers, takes approximately 13h 22m.
The distance between Mechanicsburg and Erie is 350 miles. The road distance is 265.8 miles.
The best way to get from Mechanicsburg to Erie without a car is to bus which takes 9h 52m and costs $55 - $100.
It takes approximately 9h 52m to get from Mechanicsburg to Erie, including transfers.
Mechanicsburg to Erie bus services, operated by Greyhound USA, depart from Harrisburg Bus Station.
Mechanicsburg to Erie train services, operated by Amtrak, depart from Harrisburg station.
The best way to get from Mechanicsburg to Erie is to bus which takes 9h 52m and costs $55 - $100. Alternatively, you can train, which costs $250 - $420 and takes 13h 22m.
What companies run services between Mechanicsburg, Cumberland County, PA, USA and Erie, PA, USA?
You can take a bus from E Main St & Arch St EB to Erie via Market Square Transfer Center, Harrisburg Bus Station, and Pittsburgh Intermodal Station in around 9h 52m. Alternatively, you can take a bus from E Main St & Race St EB to Erie Station via Market Square Transfer Center, Harrisburg, Pittsburgh Amtrak Station, and Cleveland Amtrak in around 13h 22m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Harrisburg to Pittsburgh Amtrak Station
- Ave. Duration
- 5h 29m
- Frequency
- Once daily
- Estimated price
- $130–210
- Website
- Amtrak
Train from Harrisburg to Pittsburgh Amtrak Station
- Ave. Duration
- 5h 29m
- Frequency
- Once daily
- Estimated price
- $130–210
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Cleveland Amtrak
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Amtrak
Train from Cleveland Amtrak to Erie Station
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Harrisburg Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 4h
- Frequency
- Every 4 hours
- Estimated price
- $35–55
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Erie
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $26–40
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Erie
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $26–40
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Harrisburg Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
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Booking & Getting There
Mechanicsburg to Erie bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Mechanicsburg to Erie train services, operated by Amtrak, arrive at Pittsburgh Amtrak Station.
Yes, the driving distance between Mechanicsburg to Erie is 266 miles. It takes approximately 5h 50m to drive from Mechanicsburg to Erie.
There are 69+ hotels available in Erie.








