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How to get fromMechanicsburg to Jacksonvilleby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), or car

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There are 4 ways to get from Mechanicsburg to Jacksonville by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly

    best
    1. Take the bus from E Main St & Race St EB to Market Square Transfer Centerbus bus
    2. Fly from Harrisburg International Airport (MDT) to Jacksonville (JAX)plane plane MDT - JAX
    5h 58m
    $183–957

  2. Bus

    cheapest
    1. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0430
    2. Take the bus from Baltimore Downtown Bus Station to Jacksonvillebus bus FlixBus N2472
    19h 17m
    $132–235

  3. Train (Amtrak)

    1. Take the train from Harrisburg to 30th Street Stationtrain train Keystone Service / ...
    2. Take the train from 30th Street Station to Jacksonvilletrain train Silver Meteor
    22h 12m
    $312–675

  4. Drive 808.4 mi

    1. Drive from Mechanicsburg to Jacksonvillecar car 808.4 mi
    13h 42m
    $148–214

Mechanicsburg to Jacksonville by bus and foot

Calendar5Weekly Services
Duration19h 17mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Mechanicsburg to Jacksonville.ExpandLaunch map view
  • Distance: 761.5 mi
  • Duration: 5h 58m

What companies run services between Mechanicsburg, Cumberland County, PA, USA and Jacksonville, FL, USA?

You can take a bus from E Main St & Arch St EB to Jacksonville via Market Square Transfer Center, Harrisburg Bus Station, and Baltimore Downtown Bus Station in around 19h 17m. Alternatively, you can take a bus from E Main St & Race St EB to Jefferson St + Beaver St via Market Square Transfer Center, Harrisburg, 30th Street Station, Jacksonville, and Amtrak Station in around 22h 12m.

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