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How to get fromMechanicsburg to South Carolinaby plane, taxi, train (Amtrak), car, bus, or train

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There are 4 ways to get from Mechanicsburg to South Carolina by plane, taxi, train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, taxi

    best
    1. Fly from Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT)plane plane MDT - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    4h 37m
    $162–594

  2. Drive 603.5 mi

    cheapest
    1. Drive from Mechanicsburg to Charlestoncar car 603.5 mi
    11h 24m
    $111–160

  3. Train (Amtrak)

    1. Take the train from Harrisburg to 30th Street Stationtrain train Keystone Service / ...
    2. Take the train from 30th Street Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    17h
    $251–532

  4. Bus, train, taxi

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus
    2. Take the train from Washington Union Station to Savannah Stationtrain train
    3. Take the taxi from Savannah Station to Bluffton Transfer Centertaxi taxi
    4. Take the bus from Bluffton Transfer Center to Walmartbus bus 320
    5. Take the taxi from Walmart to Dorchester Village Shopping Center Park & Ridetaxi taxi
    23h 32m

Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT) flights

Calendar81Weekly Planes
Duration2h 41mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Mechanicsburg to South Carolina.ExpandLaunch map view
  • Distance: 459 mi
  • Duration: 4h 37m

What companies run services between Mechanicsburg, Cumberland County, PA, USA and South Carolina, USA?

You can take a bus from E Main St & Race St EB to Charleston via Market Square Transfer Center, Harrisburg, 30th Street Station, and Charleston Amtrak Station in around 17h.

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