Rome2Rio

How to get fromMedellín to Cayo Santa Maríaby plane or bus

Find Transport to Cayo Santa María

See all options

There are 2 ways to get from Medellín to Cayo Santa María by plane or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Abel Santamaría Airport, bus

    best
    1. Fly from Medellin Jose Marie Cordova (MDE) to Abel Santamaría Airport (SNU)plane plane MDE - SNU
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus
    12h 51m
    $170–687

  2. Fly to José Martí International Airport, bus

    1. Fly from Medellin Jose Marie Cordova (MDE) to José Martí International Airport (HAV)plane plane MDE - HAV
    2. Take the bus from Havana Airport to Matanzasbus bus
    3. Take the bus from Matanzas to Santa Clarabus bus
    4. Take the bus from Santa Clara to Cayo Santa Maríabus bus
    18h 7m
    $270–692

Medellin Jose Marie Cordova (MDE) to Abel Santamaría Airport (SNU) flights

Calendar7Weekly Planes
Duration6h 45mAverage Duration
Ticket$118Cheapest Price
See schedules

Questions & Answers

Map of how to get from Medellín to Cayo Santa María.ExpandLaunch map view
  • Distance: 2,028.6 km
  • Duration: 12h 51m

What companies run services between Medellín, Colombia and Cayo Santa María, Villa Clara, Cuba?

There is no direct connection from Medellín to Cayo Santa María. However, you can take the taxi to Medellin Jose Marie Cordova Airport, walk to Medellin Jose Marie Cordova (MDE) airport, fly to Abel Santamaría Airport (SNU), take the taxi to Santa Clara, then take the bus to Cayo Santa María. Alternatively, you can take the taxi to Medellin Jose Marie Cordova Airport, walk to Medellin Jose Marie Cordova (MDE) airport, fly to José Martí International Airport (HAV), walk to Havana Airport, take the bus to Matanzas, take the bus to Santa Clara, take the bus to Vc, walk to Santa Clara, then take the bus to Cayo Santa María.

Airlines
Bus operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including South Korea: Travelling from Seoul to Busan , Italy Travel Guides, and What documents do I need to cross Niagara Falls? - to help you get the most out of your next trip.