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How to get fromMedellín to Guayaquilby plane, taxi, bus, or car

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There are 6 ways to get from Medellín to Guayaquil by plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Medellin Jose Marie Cordova

    best
    1. Fly from Medellin Jose Marie Cordova (MDE) to José Joaquín De Olmedo International Airport (GYE)plane plane MDE - GYE
    4h 40m
    $249–524

  2. Drive 1,496.2 km

    cheapest
    1. Drive from Medellín to Guayaquilcar car 1,496.2 km
    25h 19m
    $85–123

  3. Taxi, bus via Quito Terminal Carcelén

    1. Take the taxi from Medellín to Rumichacataxi taxi
    2. Take the bus from Rumichaca to Terminal Terrestre Quitumbebus bus
    3. Take the bus from Quito Terminal Carcelén to Guayaquilbus bus
    27h 33m
    $826–856

  4. Fly from Enrique Olaya Herrera Airport

    1. Fly from Enrique Olaya Herrera Airport (EOH) to José Joaquín De Olmedo International Airport (GYE)plane plane EOH - GYE
    6h 45m
    $360–1,500

  5. Taxi, bus

    1. Take the taxi from Medellín to Rumichacataxi taxi
    2. Take the bus from Rumichaca to Terminal Terrestre Quitumbebus bus
    3. Take the bus from Terminal Terrestre Quitumbe to Guayaquilbus bus
    30h 44m
    $822–845

  6. Bus

    1. Take the bus from Terminal del Sur to Terminal de Transporte Calibus bus
    2. Take the bus from Terminal de Transporte Cali to Ipialesbus bus
    3. Take the bus from Rumichaca to Terminal Terrestre Quitumbebus bus
    4. Take the bus from Terminal Terrestre Quitumbe to Duránbus bus
    38h 25m
    $88–143

Medellin Jose Marie Cordova (MDE) to José Joaquín De Olmedo International Airport (GYE) flights

Calendar50Weekly Planes
Duration4h 2mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Medellín to Guayaquil.ExpandLaunch map view
  • Distance: 1,070.9 km
  • Duration: 4h 40m

What companies run services between Medellín, Colombia and Guayaquil, Ecuador?

Avianca - Aerovías del Continente Americano S.A. and Copa Airlines fly from Medellin Jose Marie Cordova (MDE) to José Joaquín De Olmedo International Airport (GYE) every 4 hours. Alternatively, you can take a bus from Terminal del Sur to Durán via Terminal de Transporte Cali, Ipiales, Terminal Ipiales, Rumichaca, and Terminal Terrestre Quitumbe in around 38h 25m.

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