There are 6 ways to get from Medellín to Los Santos by plane, bus, ferry, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Medellin Jose Marie Cordova to Tocumen International Airport, bus
best- Fly from Medellin Jose Marie Cordova (MDE) to Tocumen International Airport (PTY)plane MDE - PTY
- Take the bus from La Chorrera to Chitrébus
9h 49m$287–494Fly Enrique Olaya Herrera Airport to Tocumen International Airport, bus
cheapest- Fly from Enrique Olaya Herrera Airport (EOH) to Tocumen International Airport (PTY)plane EOH - PTY
- Take the bus from La Chorrera to Chitrébus
11h 9m$181–699Bus, ferry, Tour, taxi
- Take the bus from Terminal del Norte to Necoclíbus
- Take the ferry from Necocli to Sapzurroferry
- Take the ferry from Sapzurro to Cartíferry
- Take the taxi from Cartí to El Llanotaxi
- Take the bus from El Llano to Albrookbus
- Take the bus from Panama City - Albrook to Chitrébus
5d 19hFly Medellin Jose Marie Cordova to Panama Pacific International Airport, bus
- Fly from Medellin Jose Marie Cordova (MDE) to Panama Pacific International Airport (BLB)plane MDE - BLB
- Take the bus from Albrook to Antónbus
- Take the bus from Antón to Chitrébus
9h 23mTaxi to Pereira, fly to Tocumen International Airport, bus
- Take the taxi from Medellín to Pereirataxi
- Fly from Pereira (PEI) to Tocumen International Airport (PTY)plane PEI - PTY
- Take the bus from La Chorrera to Chitrébus
14h 55m$331–592Taxi, ferry, Tour, bus
- Take the taxi from Medellín to Necoclítaxi
- Take the ferry from Necocli to Sapzurroferry
- Take the ferry from Sapzurro to Cartíferry
- Take the taxi from Cartí to El Llanotaxi
- Take the bus from El Llano to Albrookbus
- Take the bus from Panama City - Albrook to Chitrébus
5d 19h
Medellin Jose Marie Cordova (MDE) to Tocumen International Airport (PTY) flights
Questions & Answers
The cheapest way to get from Medellín to Los Santos is to fly and bus which costs $280 - $500 and takes 9h 49m.
The fastest way to get from Medellín to Los Santos is to fly and bus which takes 9h 49m and costs $280 - $500.
The distance between Medellín and Los Santos is 845 km.
The best way to get from Medellín to Los Santos without a car is to bus and ferry and Tour and taxi which takes 5 days 19h and costs .
It takes approximately 9h 49m to get from Medellín to Los Santos, including transfers.
There are 48+ hotels available in Los Santos.
What companies run services between Medellín, Colombia and Los Santos, Panama?
There is no direct connection from Medellín to Los Santos. However, you can take the taxi to Medellin Jose Marie Cordova Airport, walk to Medellin Jose Marie Cordova (MDE) airport, fly to Tocumen International Airport (PTY), walk to Aeropuerto Internacional de Tocumen, take the shuttle to La Chorrera, walk to La Chorrera, take the bus to Chitré, then take the taxi to Los Santos. Alternatively, you can take the bus to Necoclí, walk to Necocli, take the ferry to Sapzurro, walk to Sapzurro, take the ferry to Cartí, take the taxi to El Llano, take the bus to Albrook, take the bus to Chitré, then take the taxi to Los Santos.
- Website
- copaair.com
Flights from Medellin Jose Marie Cordova to Tocumen International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $35–240
Flights from Enrique Olaya Herrera Airport to Tocumen International Airport via Pereira
- Ave. Duration
- 4h 26m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
Flights from Enrique Olaya Herrera Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $120–1,200
Flights from Enrique Olaya Herrera Airport to Tocumen International Airport via Cali
- Ave. Duration
- 4h 49m
- When
- Saturday, Monday, Wednesday, and Thursday
- Estimated price
- $130–700
Flights from Pereira to Tocumen International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $50–310
- Website
- avianca.com
Flights from Medellin Jose Marie Cordova to Tocumen International Airport via Bogota
- Ave. Duration
- 3h 38m
- When
- Every day
- Estimated price
- $180–320
Flights from Enrique Olaya Herrera Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 5h 45m
- When
- Monday to Friday
- Estimated price
- $360–1,600
Flights from Pereira to Tocumen International Airport via Bogota
- Ave. Duration
- 3h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–800
- Website
- turkishairlines.com
Flights from Medellin Jose Marie Cordova to Tocumen International Airport
- Ave. Duration
- 1h 27m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- $35–240
Flights from Enrique Olaya Herrera Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 3h 50m
- When
- Wednesday and Friday
- Estimated price
- $310–1,200
- Website
- copaair.com
Flights from Medellin Jose Marie Cordova to Panama Pacific International Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $100–130
- Phone
- +507 314 6204
- Website
- instagram.com
Bus from La Chorrera to Chitré
- Ave. Duration
- 3h 19m
- Frequency
- Hourly
- Estimated price
- $9
- Schedules at
- grantnt.com
Bus from Panama City - Albrook to Chitré
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $9
- Schedules at
- grantnt.com
Bus from Antón to Chitré
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- $8
- Schedules at
- grantnt.com
Bus from La Chorrera to Chitré
- Ave. Duration
- 3h 19m
- Frequency
- Hourly
- Estimated price
- $9
- Schedules at
- grantnt.com
Bus from La Chorrera to Chitré
- Ave. Duration
- 3h 19m
- Frequency
- Hourly
- Estimated price
- $9
- Schedules at
- grantnt.com
Bus from Panama City - Albrook to Chitré
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $9
- Schedules at
- grantnt.com
- Phone
- +57 604 4448 6641
- [email protected]
- Website
- cootransuroccidente.com
Bus from Terminal del Norte to Necoclí
- Ave. Duration
- 7h 45m
- Frequency
- Hourly
- Estimated price
- $30–45
- Schedules at
- cootransuroccidente.com
- Book at
- cootransuroccidente.com
- Phone
- +57 604 448 7712
- [email protected]
- Website
- transportesgomezhernandez.com
Bus from Terminal del Norte to Necoclí
- Ave. Duration
- 9h
- Frequency
- Every 3 hours
- Estimated price
- $18–40
- Schedules at
- transportesgomezhernandez.com
- Phone
- +57 604 444 5873
- [email protected]
- Website
- sotrauraba.com
Bus from Terminal del Norte to Necoclí
- Ave. Duration
- 8h
- Frequency
- 5 times a day
- Estimated price
- $31
- Schedules at
- sotrauraba.com
- Phone
- +507 303 3030
- Website
- Sindicato Unido Darien
Bus from El Llano to Albrook
- Ave. Duration
- 1h 43m
- Frequency
- 5 times a day
- Schedules at
- Sindicato Unido Darien
Bus from El Llano to Albrook
- Ave. Duration
- 1h 43m
- Frequency
- 5 times a day
- Schedules at
- Sindicato Unido Darien
- Phone
- +507 314 6235
- [email protected]
- Website
- instagram.com
Bus from Panama City - Albrook to Chitré
- Ave. Duration
- 5h
- Frequency
- Every 3 hours
- Estimated price
- $9
- Schedules at
- grantnt.com
Bus from Panama City - Albrook to Chitré
- Ave. Duration
- 5h
- Frequency
- Every 3 hours
- Estimated price
- $9
- Schedules at
- grantnt.com
- Phone
- +507 775-2974
- [email protected]
- Website
- Terminales Panama David
Bus from Albrook to Antón
- Ave. Duration
- 2h 8m
- Frequency
- Hourly
- Schedules at
- Terminales Panama David
- Phone
- +57 604 784 9194
- [email protected]
- Website
- transportesluz.com
Ferry from Necocli to Sapzurro
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Schedules at
- transportesluz.com
Ferry from Necocli to Sapzurro
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Schedules at
- transportesluz.com
- Phone
- +57 313 716 6662
- [email protected]
- Website
- San Blas Adventures
Ferry from Sapzurro to Cartí
- Ave. Duration
- 5d
- Frequency
- On demand
- Estimated price
- $545
- Website
- San Blas Adventures
Ferry from Sapzurro to Cartí
- Ave. Duration
- 5d
- Frequency
- On demand
- Estimated price
- $545
- Website
- San Blas Adventures
- Ave. Duration
- 3h 37m
- Estimated price
- $13–517
Tax Individual
- Phone
- +57 604 444 4444
- Website
- tax-individual.com.co
Tax Individual
- Phone
- +57 604 444 4444
- Website
- tax-individual.com.co
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