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How to get fromMedford to Niagara Fallsby plane, bus, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)

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There are 8 ways to get from Medford to Niagara Falls by plane, bus, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport, bus

    best
    1. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    5h 12m
    $90–514

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Boston to Buffalobus bus Greyhound US0171
    13h 1m
    $77–149

  3. Train

    1. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    2. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train Empire Service / ...
    14h 49m
    $161–482

  4. Drive 467.3 mi

    1. Drive from Medford to Niagara Fallscar car 467.3 mi
    8h 15m
    $86–124

  5. Fly to Rochester, bus

    1. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    2. Take the bus from Rochester Bus Stop to Niagara Falls USAbus bus
    6h 41m
    $123–603

  6. Fly to Toronto Island Airport, bus

    1. Fly from Boston Logan Airport (BOS) to Toronto Island Airport (YTZ)plane plane BOS - YTZ
    2. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    7h 35m
    $122–540

  7. Fly to Toronto Pearson International Airport, bus

    1. Fly from Boston Logan Airport (BOS) to Toronto Pearson International Airport (YYZ)plane plane BOS - YYZ
    2. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    7h 56m
    $128–619

  8. Bus via Ithaca (Flixbus)

    1. Take the bus from Boston to Ithacabus bus FlixBus 2691
    2. Take the bus from Ithaca to Niagara Falls USAbus bus FlixBus 2685 / ...
    14h 46m
    $91–152

Medford to Niagara Falls by bus, subway, and foot (Greyhound)

Calendar14Weekly Services
Duration13h 1mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

Map of how to get from Medford to Niagara Falls.ExpandLaunch map view
  • Distance: 433.2 mi
  • Duration: 5h 12m

What companies run services between Medford, MA, USA and Niagara Falls, NY, USA?

Greyhound USA operates a bus from Boston to Buffalo twice daily. Tickets cost $70–140 and the journey takes 10h 5m. Alternatively, you can take a subway from Wellington to Niagara Falls Amtrak Station via Back Bay, Boston, and Buffalo Depew Station in around 14h 49m.

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