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How to get fromMedford to Des Moinesby plane, bus (Amtrak, Greyhound), bus, train, or car

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There are 5 ways to get from Medford to Des Moines by plane, bus (Amtrak, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Rogue Valley International - Medford Airport (MFR) to Des Moines (DSM)plane plane MFR - DSM
    5h 32m
    $178–694

  2. Fly to Fort Dodge Municipal Airport, drive

    cheapest
    1. Fly from Rogue Valley International - Medford Airport (MFR) to Fort Dodge Municipal Airport (FOD)plane plane MFR - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar car
    15h 46m
    $112–427

  3. Bus

    1. Take the bus from Medford Airport to Klamath Fallsbus bus
    2. Take the bus from Greyhound Connection To Medford Via The Shuttle Klamath Falls + Amtrak Klamath Falls Rail Station to Corner Of Main And West Fifth Avebus bus
    3. Take the bus from Corner Of Main And West Fifth Ave to Amtrak Renobus bus
    4. Take the bus from Sparks Transit Center to Denver Union Stationbus bus
    5. Take the bus from Denver Union Station to Des Moinesbus bus
    45h 38m
    $306–605

  4. Bus, train

    1. Take the bus from Medford to JCT Transit Hub - 300 NW 5th St - Rt 100bus bus 100
    2. Take the bus from Grants Pass to Portland Curbside Bus Stopbus bus
    3. Take the train from Portland to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Des Moinesbus bus
    2d 3h
    $651–1,367

  5. Drive 1,784.1 mi

    1. Drive from Medford to Des Moinescar car 1,784.1 mi
    29h 47m
    $326–471

Medford to Des Moines by bus

Calendar1Weekly Buses
Duration45h 38mAverage Duration
Ticket$306Cheapest Price
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Questions & Answers

Map of how to get from Medford to Des Moines.ExpandLaunch map view
  • Distance: 1,502 mi
  • Duration: 5h 32m

What companies run services between Medford, OR, USA and Des Moines, IA, USA?

United Airlines, Allegiant Air, and two other airlines fly from Rogue Valley International - Medford Airport (MFR) to Des Moines (DSM) 4 times a day. Alternatively, you can take a bus from Medford Airport to Des Moines via Klamath Falls, Greyhound Connection To Medford Via The Shuttle Klamath Falls + Amtrak Klamath Falls Rail Station, Corner Of Main And West Fifth Ave, Amtrak Reno, RTC 4th STREET STATION Bay I 4SS, Sparks Transit Center, and Denver Union Station in around 45h 38m.

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