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How to get fromMedford to Irvineby plane, bus (Greyhound), bus, train, or car

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There are 4 ways to get from Medford to Irvine by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Rogue Valley International - Medford Airport (MFR) to John Wayne Airport Orange County (SNA)plane plane MFR - SNA
    1h 59m
    $230–370

  2. Bus

    cheapest
    1. Take the bus from Medford to JCT Transit Hub - 300 NW 5th St - Rt 100bus bus 100
    2. Take the bus from Grants Pass to Sacramento Bus Stationbus bus
    3. Take the bus from Sacramento Bus Station to Anaheim Regional Transportation Intermodal Centerbus bus
    23h 52m
    $118–234

  3. Bus, train

    1. Take the bus from Medford Airport to Klamath Fallsbus bus
    2. Take the train from Klamath Falls to Los Angelestrain train
    3. Take the train from L.A. Union Station to Tustintrain train
    27h 48m
    $299–654

  4. Drive 729.7 mi

    1. Drive from Medford to Irvinecar car 729.7 mi
    12h 7m
    $134–193

Medford to Irvine by bus and foot

Calendar7Weekly Services
Duration23h 52mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from Medford to Irvine.ExpandLaunch map view
  • Distance: 659.1 mi
  • Duration: 1h 59m

What companies run services between Medford, OR, USA and Irvine, CA, USA?

Allegiant Air, Alaska Airlines, Inc., and two other airlines fly from Rogue Valley International - Medford Airport (MFR) to John Wayne Airport Orange County (SNA) every 4 hours. Alternatively, you can take a bus from Medford to Main-Harvard via JCT Transit Hub - 300 NW 5th St - Rt 100, Grants Pass, Sacramento Bus Station, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 23h 52m.

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