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How to get fromMedford to Lake Siskiyouby bus (Greyhound), bus, train, car, or bus (Amtrak, Greyhound)

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There are 4 ways to get from Medford to Lake Siskiyou by bus (Greyhound), bus, train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Grants Pass

    best
    1. Take the bus from Medford to JCT Transit Hub - 300 NW 5th St - Rt 100bus bus 100
    2. Take the bus from Grants Pass to Mt Shastabus bus Greyhound US0500
    4h 49m
    $32–54
  2. Drive 90.8 mi

    cheapest
    1. Drive from Medford to Lake Siskiyoucar car 90.8 mi
    1h 41m
    $17–24
  3. Bus, train

    1. Take the bus from Medford Airport to Klamath Fallsbus bus Grants Pass
    2. Take the train from Klamath Falls to Dunsmuir Amtrak Stationtrain train Coast Starlight
    5h 35m
    $76–157
  4. Bus

    1. Take the bus from Front Street Station - Medford to Newman United Methodist Church - Grants Passbus bus SouthWest
    2. Take the bus from Grants Pass to Mt Shastabus bus Greyhound US0500
    5h 24m
    $39–94

Questions & Answers

What companies run services between Medford, OR, USA and Lake Siskiyou, CA, USA?

You can take a bus from Medford to Lake Siskiyou via JCT Transit Hub - 300 NW 5th St - Rt 100, Grants Pass, and Mt Shasta in around 4h 49m.

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Bus operators

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