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How to get fromMedford to San Diegoby plane, bus (Greyhound), bus, train, or car

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There are 5 ways to get from Medford to San Diego by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Rogue Valley International - Medford Airport (MFR) to San Diego International Airport (SAN)plane plane MFR - SAN
    2h 19m
    $130–400

  2. Bus

    1. Take the bus from Medford to JCT Transit Hub - 300 NW 5th St - Rt 100bus bus 100
    2. Take the bus from Grants Pass to Sacramento Bus Stationbus bus
    3. Take the bus from Sacramento Bus Station to San Diego Greyhound Bus Stopbus bus
    25h 1m
    $131–257

  3. Bus, train

    1. Take the bus from Medford Airport to Klamath Fallsbus bus
    2. Take the train from Klamath Falls to Los Angelestrain train
    3. Take the train from Los Angeles to San Diegotrain train
    29h 35m
    $306–727

  4. Drive 810.4 mi

    1. Drive from Medford to San Diegocar car 810.4 mi
    13h 29m
    $148–214

  5. Bus, train via Front Street Station - Medford

    1. Take the bus from Front Street Station - Medford to Klamath Falls Amtrak Stationbus bus
    2. Take the train from Klamath Falls to Los Angelestrain train
    3. Take the bus from Los Angeles to San Diegobus bus
    30h 53m
    $316–703

Medford to San Diego by bus, foot, and tram

Calendar7Weekly Services
Duration25h 1mAverage Duration
Ticket$131Cheapest Price
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Questions & Answers

Map of how to get from Medford to San Diego.ExpandLaunch map view
  • Distance: 734.4 mi
  • Duration: 2h 19m

What companies run services between Medford, OR, USA and San Diego, CA, USA?

Alaska Airlines, Inc., United Airlines, and American Airlines fly from Rogue Valley International - Medford Airport (MFR) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a bus from Medford to County Center/Little Italy Station via JCT Transit Hub - 300 NW 5th St - Rt 100, Grants Pass, Sacramento Bus Station, San Diego Greyhound Bus Stop, and Old Town Station in around 25h 1m.

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