There are 7 ways to get from Medford to Sisters by bus (Amtrak), car, plane, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Medford Airport to Klamath Fallsbus Grants Pass
- Take the bus from Klamath Falls Amtrak Station to Bend Hawthorne Stationbus Hwy 97 Connector
7h 41m$29–95Drive 194.3 mi
- Drive from Medford to Sisterscar 194.3 mi
4h$36–52Fly to Roberts Field-Redmond Municipal Airport
- Fly from Rogue Valley International - Medford Airport (MFR) to Roberts Field-Redmond Municipal Airport (RDM)plane MFR - RDM
5h 29m$47–238Bus, train
- Take the bus from Medford Airport to Klamath Fallsbus
- Take the train from Klamath Falls to Chemulttrain
- Take the bus from Chemult Post Office to Hawthorne Main Transfer Stationbus
8h 17m$38–120Bus via Front Street Station - Medford
- Take the bus from Front Street Station - Medford to Klamath Falls Amtrak Stationbus SouthWest
- Take the bus from Klamath Falls Amtrak Station to Bend Hawthorne Stationbus Hwy 97 Connector
8h 51m$34–96Fly to Mahlon Sweet Field Airport, bus
- Fly from Rogue Valley International - Medford Airport (MFR) to Mahlon Sweet Field Airport (EUG)plane MFR - EUG
- Take the bus from Eugene Amtrak Bus Platform to Sisters Mobility Hubbus
7h 20m$483–601Fly to Portland International Airport, bus
- Fly from Rogue Valley International - Medford Airport (MFR) to Portland International Airport (PDX)plane MFR - PDX
- Take the bus from Portland International Airport to Redmond Hubbus
6h 56m$213–384
Medford to Sisters by bus
Questions & Answers
The cheapest way to get from Medford to Sisters is to drive which costs $35 - $55 and takes 4h.
The fastest way to get from Medford to Sisters is to drive which takes 4h and costs $35 - $55.
No, there is no direct bus from Medford to Sisters. However, there are services departing from Medford Airport and arriving at Main Avenue @ Oak Street via Klamath Falls Amtrak Station and Platform A @ Hawthorne Station. The journey, including transfers, takes approximately 7h 41m.
The distance between Medford and Sisters is 245 miles. The road distance is 195.5 miles.
The best way to get from Medford to Sisters without a car is to bus which takes 7h 41m and costs $29 - $100.
It takes approximately 7h 41m to get from Medford to Sisters, including transfers.
Medford to Sisters bus services, operated by Amtrak Thruway, depart from Medford Airport station.
The best way to get from Medford to Sisters is to bus which takes 7h 41m and costs $29 - $100. Alternatively, you can fly, which costs $45 - $240 and takes 5h 29m.
Medford to Sisters bus services, operated by Amtrak Thruway, arrive at Klamath Falls station.
Yes, the driving distance between Medford to Sisters is 195 miles. It takes approximately 4h to drive from Medford to Sisters.
What companies run services between Medford, OR, USA and Sisters, OR, USA?
You can take a bus from Medford Airport to Main Avenue @ Oak Street via Klamath Falls Amtrak Station, Bend Hawthorne Station, and Platform A @ Hawthorne Station in around 7h 41m. Alternatively, Alaska Airlines, Inc., United Airlines, and Delta fly from Rogue Valley International - Medford Airport (MFR) to Roberts Field-Redmond Municipal Airport (RDM) every 3 hours.
- Website
- alaskaair.com
Flights from Rogue Valley International - Medford Airport to Roberts Field-Redmond Municipal Airport via Portland International Airport
- Ave. Duration
- 3h 4m
- When
- Every day
- Estimated price
- $110–650
Flights from Rogue Valley International - Medford Airport to Roberts Field-Redmond Municipal Airport via Seattle
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $120–650
Flights from Rogue Valley International - Medford Airport to Roberts Field-Redmond Municipal Airport via San Diego
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $140–650
Flights from Rogue Valley International - Medford Airport to Roberts Field-Redmond Municipal Airport via Los Angeles
- Ave. Duration
- 5h 54m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–650
Flights from Rogue Valley International - Medford Airport to Mahlon Sweet Field Airport via Portland International Airport
- Ave. Duration
- 3h 4m
- When
- Every day
- Estimated price
- $470–600
Flights from Rogue Valley International - Medford Airport to Mahlon Sweet Field Airport via Seattle
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $470–600
Flights from Rogue Valley International - Medford Airport to Mahlon Sweet Field Airport via San Diego
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $470–600
Flights from Rogue Valley International - Medford Airport to Portland International Airport
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- $150–320
- Website
- delta.com
Flights from Rogue Valley International - Medford Airport to Roberts Field-Redmond Municipal Airport via Seattle
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $40–240
Flights from Rogue Valley International - Medford Airport to Mahlon Sweet Field Airport via Seattle
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $40–230
Flights from Rogue Valley International - Medford Airport to Mahlon Sweet Field Airport via Salt Lake City
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $65–300
- Website
- united.com
Flights from Rogue Valley International - Medford Airport to Roberts Field-Redmond Municipal Airport via San Francisco
- Ave. Duration
- 5h 13m
- When
- Tuesday, Wednesday, Saturday, Thursday, and Sunday
- Estimated price
- $50–260
Flights from Rogue Valley International - Medford Airport to Mahlon Sweet Field Airport via San Francisco
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $50–250
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Klamath Falls to Chemult
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- $23–50
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Medford Airport to Klamath Falls
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $16–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $16–45
Bus from Medford Airport to Klamath Falls
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $16–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $16–45
Bus from Front Street Station - Medford to Klamath Falls Amtrak Station
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $21–45
- Phone
- +1 888-846-4183
- Website
- oregon-point.com
Bus from Medford Airport to Klamath Falls
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $11–29
- Website
- https://www.oregon-point.com
Bus from Medford Airport to Klamath Falls
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $11–29
- Website
- https://www.oregon-point.com
Bus from Front Street Station - Medford to Klamath Falls Amtrak Station
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- $15–35
- Website
- https://www.oregon-point.com
- Phone
- +1 541-366-5110
- [email protected]
- Website
- pacificcrestbuslines.net
Bus from Klamath Falls Amtrak Station to Bend Hawthorne Station
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $15–50
- Website
- https://pacificcrestbuslines.net
Bus from Chemult Post Office to Hawthorne Main Transfer Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $7–25
- Website
- https://pacificcrestbuslines.net
Bus from Klamath Falls Amtrak Station to Bend Hawthorne Station
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $15–50
- Website
- https://pacificcrestbuslines.net
Bus from Eugene Amtrak Bus Platform to Sisters Mobility Hub
- Ave. Duration
- 2h 3m
- Frequency
- Once daily
- Estimated price
- $10–35
- Website
- https://pacificcrestbuslines.net
- Phone
- +1 541 883-2877
- [email protected]
- Website
- basintransit.com
Bus from Chemult Post Office to Hawthorne Main Transfer Station
- Ave. Duration
- 1h 51m
- Frequency
- Once daily
- Estimated price
- $2
- Website
- https://www.basintransit.com
- Schedules at
- https://www.basintransit.com/routes-and-schedules#Shedules
- Phone
- (541) 389-7469
- [email protected]
- Website
- cobreeze.com
Bus from Portland International Airport to Redmond Hub
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $57–61
- Website
- https://cobreeze.com/
- Schedules at
- https://cobreeze.com/schedule/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 189+ hotels available in Sisters.













